TAPS
TAPS (CAS 29915-38-6), empirical formula C7H17NO6S, is a versatile biological buffer. With a molecular weight of 243.28 g/mol, it offers excellent buffering capacity in the slightly alkaline range (pH 7.7-9.1). TAPS is highly soluble in water and is particularly suited for applications in cell culture due to its proven suitability in such systems. It is a valuable reagent for biochemical and biological research requiring stable pH control.
- IUPAC
- N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid,[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid
- Synonyms
- N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid

Biological Buffering Agent
TAPS is widely employed as a biological buffer in various research applications, maintaining stable pH conditions crucial for enzyme activity and cellular processes. Its useful pH range of 7.7 to 9.1 makes it suitable for experiments requiring a slightly alkaline environment.
Cell Culture Applications
This buffer is tested for suitability in cell culture, ensuring it does not adversely affect cell viability or growth. Researchers utilise TAPS to provide a controlled physiological environment for maintaining cell lines in vitro.
Biochemical Assays
Its consistent buffering capacity across its effective pH range makes TAPS valuable for various biochemical assays where precise pH control is critical for reaction kinetics and product formation.
| Molecular weight | 243.28 |
|---|---|
| Empirical formula | C7H17NO6S |
| Assay | ≥99.5% (titration) |
| Suitability | cell culture tested |
| Melting point | 230-235 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Cation traces | heavy metals (as Pb): ≤5 ppm |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Useful Ph Range | 7.7 - 9.1 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is TAPS used for?
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TAPS is primarily used as a biological buffer in research, particularly for maintaining stable pH in the range of 7.7-9.1, and is tested for suitability in cell culture applications.
What are the CAS number and chemical formula for TAPS?
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The CAS number for TAPS is 29915-38-6 and its empirical formula is C7H17NO6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies TAPS with an assay of ≥99.5% (titration) and it is tested for suitability in cell culture. TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling TAPS?
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TAPS should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Refer to the Safety Data Sheet for comprehensive handling information. It has a flash point of >110 °C and is classified under WGK Germany 3.
How is TAPS packed, shipped, and exported?
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TAPS is carefully packed to maintain its integrity during transit. Tech Serve Solutions is experienced in global export and can arrange shipment worldwide, adhering to all relevant regulations.
How can I request a sample or quote for TAPS?
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To request a sample or a quote for TAPS, please visit our website or contact our sales team directly with your specific requirements.
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