TABS
TABS (CAS 54960-65-5), a zwitterionic N-tris(Hydroxymethyl)methyl-4-aminobutanesulfonic acid derivative, is a Good's buffer with a useful pH range of 8.2-9.6. Its molecular formula is C8H19NO6S, and it has a molecular weight of 257.30 g/mol. This compound is primarily employed in biochemical and biological research as a buffering agent due to its capacity to maintain stable pH conditions in aqueous solutions.
- IUPAC
- N-tris(Hydroxymethyl)methyl-4-aminobutanesulfonic acid
- Synonyms
- N-tris(Hydroxymethyl)methyl-4-aminobutanesulfonic acid

Biochemical Research
TABS serves as an effective buffer in various biochemical assays and experiments. Its pKa of 8.9 allows for precise pH control in the alkaline range, crucial for enzyme activity and protein stability studies.
Biological Buffering Systems
Utilised in the preparation of biological buffers, TABS helps maintain physiological pH conditions. This is essential for cell culture media, electrophoresis, and other biological applications where pH stability is paramount.
Laboratory Reagent
As a laboratory reagent, TABS is supplied for general research and analytical purposes. Its defined chemical properties make it suitable for a wide array of scientific investigations.
| Molecular weight | 257.30 |
|---|---|
| Empirical formula | C8H19NO6S |
| Assay | ≥97% (titration) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Pka 25 °C | 8.9 |
|---|---|
| Ph Range | 8.2 - 9.6 |
| Useful Ph Range | 8.2 - 9.6 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is TABS used for?
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TABS is used as a biological buffer and a laboratory reagent, particularly in biochemical research. Its useful pH range is 8.2-9.6, with a pKa of 8.9 at 25°C.
What are the CAS number and formula for TABS?
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The CAS number for TABS is 54960-65-5, and its empirical formula is C8H19NO6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies TABS with an assay of ≥97% (titration). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated.
What are the safety precautions for handling TABS?
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When handling TABS, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound is classified with WGK Germany 3.
How is TABS packed and shipped?
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TABS is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a sample or quote for TABS?
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To request a sample or a quote for TABS, please contact our sales team through the website or by phone, providing your specific requirements.
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