TG003
TG003 is a chemical compound with the CAS number 300801-52-9 and the empirical formula C13H15NO2S. This pale yellow solid has a molecular weight of 249.33. TG003 serves as a valuable tool in scientific research, particularly in the development of assays for screening substances that influence mRNA splicing. Its utility extends to cell biology, cell signaling, and neuroscience research.
- IUPAC
- (Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one

mRNA Splicing Assay Development
TG003 has been instrumental in the creation of assays designed to screen for compounds that modulate mRNA splicing processes. This application is crucial for understanding gene expression regulation.
Cell Biology Research
As a bioactive small molecule, TG003 finds application in general cell biology studies. It can be used to investigate various cellular mechanisms and signaling pathways.
Enzyme Inhibition Studies
This compound is classified as an enzyme inhibitor, specifically targeting serine/threonine kinases. Researchers utilise TG003 to explore kinase activity and its role in cellular functions.
| Molecular weight | 249.33 |
|---|---|
| Empirical formula | C13H15NO2S |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | pale yellow |
| Solubility | DMSO: soluble33 mg/mL |
| Storage temperature | 2-8°C |
| Melting point | 132-132.5 °C |
| Application | TG003 has been used to develop assays for screening substances that affect mRNA splicing1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is TG003 used for?
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TG003 is primarily used for developing assays to screen substances that affect mRNA splicing. It is also applied in cell biology research, cell signaling, and neuroscience studies, and as a serine/threonine kinase inhibitor.
What is the CAS number and chemical formula for TG003?
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The CAS number for TG003 is 300801-52-9, and its empirical formula is C13H15NO2S.
What grade and purity does Tech Serve Solutions supply for TG003?
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Tech Serve Solutions supplies TG003 with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should TG003 be handled safely?
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TG003 is a Warning substance, classified with H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Handle in a well-ventilated area and avoid dust formation.
How is TG003 shipped and exported?
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As a global supplier and exporter of fine chemicals, Tech Serve Solutions can accommodate various shipping and export requirements for TG003. Please contact us for specific details.
How can I request a sample or quote for TG003?
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To request a sample or obtain a quote for TG003, please contact our sales department through the website or by phone.
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