TOFA

CAS 54857-86-2C19H32O4Biochemicals & Reagents

5-(Tetradecyloxy)-2-furoic acid (TOFA), CAS 54857-86-2, with the molecular formula C19H32O4 and a molecular weight of 324.45 g/mol, is a white to beige powder. This compound functions as an inhibitor of Acetyl-CoA Carboxylase (ACC). It is primarily utilised in biochemical research, particularly in studies related to cancer metabolism and fatty acid metabolism in oncogenesis.

IUPAC: 5-(Tetradecyloxy)-2-furoic acid
Synonyms: 54857-86-2

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TOFA (C19H32O4) — chemical structure, CAS 54857-86-2; Life Science, fine chemical supplied by Tech Serve Solutions

A to CAcetyl CoA-CarboxylaseBioactive Small MoleculesBiochemicals and ReagentsCancer MetabolismCancer ResearchCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymes

01 /Applications

Biochemical Research Tool

TOFA serves as a research tool for investigating the role of Acetyl-CoA Carboxylase (ACC) in cellular processes. Its inhibitory properties are valuable for dissecting metabolic pathways, particularly those related to fatty acid synthesis and cancer cell proliferation.

Cancer Metabolism Studies

Utilised in studies focusing on cancer metabolism, TOFA can be employed to explore the impact of ACC inhibition on tumour growth and survival. This research aids in understanding the specific metabolic vulnerabilities of cancer cells.

Fatty Acid Metabolism Investigation

This compound is instrumental in research concerning fatty acid metabolism, including its role in oncogenesis. By inhibiting ACC, researchers can study the downstream effects on lipid biosynthesis and cellular signalling.

Insulin Secretion Research

As an ACC inhibitor, TOFA has been used in experimental settings to investigate its effect on insulin secretion in cell models, such as INS-1E cells, contributing to the understanding of metabolic regulation.

02 /Properties

Molecular weight	324.45
Empirical formula	C19H32O4
Assay	≥98% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: soluble2 mg/mL, clear
Storage temperature	−20°C
Melting point	112-115 °C
Application	TOFA has been used as an ACC inhibitor to study its effect on insulin secretion in INS-1E cells1.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	2

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

54857-86-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is TOFA used for?

TOFA (5-(Tetradecyloxy)-2-furoic acid) is used as a research chemical, primarily as an inhibitor of Acetyl-CoA Carboxylase (ACC). It is valuable in studies of cancer metabolism, fatty acid metabolism, and its effects on insulin secretion.

What are the CAS number and formula for TOFA?

The CAS number for TOFA is 54857-86-2, and its molecular formula is C19H32O4.

What grade and purity does Tech Serve Solutions supply for TOFA?

Tech Serve Solutions supplies TOFA with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, nutraceutical, or food grade.

How should TOFA be handled and stored?

TOFA should be handled with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the compound at -20°C.

Is TOFA a controlled substance?

The provided data does not indicate that TOFA (CAS 54857-86-2) is a controlled substance.

How is TOFA packed and exported?

TOFA is typically supplied as a white to beige powder. Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging for safe international shipment.

How can I request a quote or sample for TOFA?

To request a quote or sample of TOFA, please contact Tech Serve Solutions directly through our website or sales channels, providing the product name and CAS number (54857-86-2).