TRIS hydrochloride
TRIS hydrochloride (CAS 1185-53-1), molecular formula NH2C(CH2OH)3 · HCl, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- TRIS HCl,TRIS hydrochloride,Tris(hydroxymethyl)aminomethane hydrochloride

| Molecular weight | 157.60 |
|---|---|
| Linear formula | NH2C(CH2OH)3 · HCl |
| Assay | ≥99.0% (titration) |
| Grade | Non-Compendial |
| Form | powder |
| Solubility | H2O: soluble667 mg/mL |
| pH | 2.5-4.0 (25 °C, 4 M in H2O) |
| Melting point | 150-152 °C |
| Loss on drying | ≤0.2% loss on drying, 110 °C |
| Impurities tested | DNAse, Exonuclease; NICKase, Endonuclease; RNAse and Protease, none detectedendotoxin and total aerobic microbial count, tested≤0.5% water (Karl Fischer) |
| Suitability | cell culture testedsuitable for electrophoresis |
| Biological source | from synthetic |
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Cation traces | heavy metals (as Pb): ≤5 ppm |
| Anion traces | sulfate (SO42-): ≤50 mg/kg |
| Ignition residue | ≤0.2% (as SO4) |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | ELITE |
|---|---|
| Product Line | PharmaGrade |
| Foreign Activity | Cytotoxicity, DNase, NICKase, RNase, and Protease; tested |
| Uv Absorption | λ: 260 nm Amax: 0.12λ: 280 nm Amax: 0.08 |
| Absorption | A40%/290 ≤0.05 |
| Useful Ph Range | 7.0 - 9.0 |
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is TRIS hydrochloride?
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TRIS hydrochloride (CAS 1185-53-1), molecular formula NH2C(CH2OH)3 · HCl, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to USP, BP and EP standards.
What grades of TRIS hydrochloride does Tech Serve Solutions supply?
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Tech Serve Solutions supplies TRIS hydrochloride in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of TRIS hydrochloride?
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TRIS hydrochloride has CAS number 1185-53-1 and molecular formula NH2C(CH2OH)3 · HCl. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for TRIS hydrochloride?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of TRIS hydrochloride ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should TRIS hydrochloride be stored?
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Store TRIS hydrochloride in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is TRIS hydrochloride used for?
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TRIS hydrochloride is used in biochemicals & reagents applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for TRIS hydrochloride?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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