Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate
Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate (CAS: 25612-73-1) is a non-hydrolyzable ATP analogue used in biochemical research. With a molecular weight of 506.20 (free acid basis), this compound is a key tool for investigating enzyme mechanisms and cellular signalling pathways that involve ATP. Its applications span cell biology, neuroscience, and the study of ion channels, offering researchers a stable substitute for ATP in various experimental setups.
- IUPAC
- β,γ-Imidoadenosine 5′-triphosphate lithium salt hydrate,AMP-PNP,ATP[β,γ-NH],Adenylyl imidodiphosphate lithium salt hydrate,App(NH)p
- Synonyms
- β,γ-Imidoadenosine 5′-triphosphate lithium salt hydrateC10H17N6O12P3 · xLi+ · yH2OAMP-PNPATP[β,γ-NH]Adenylyl imidodiphosphate lithium salt hydrateApp(NH)p
triphosphatelithiumsalthydrate.png&w=3840&q=75)
Biochemical Research
Utilised in studies to research the effects of monovalent cations, such as Li+, Na+, K+, NH4+, Rb+, and Cs+, on nucleic acid structures. It serves as a stable analogue to investigate cation interactions.
Cell Signaling and Neuroscience
Applied in research to understand cellular responses and neuronal processes, including studies investigating the impact of antidepressants on microglial cytokine production.
Enzyme Inhibition Studies
Serves as a valuable tool for examining the activity and inhibition of enzymes that utilise ATP as a substrate, due to its non-hydrolysable nature.
Ion Channel Research
Investigated in the context of ion channels, particularly potassium channel modulators, contributing to the understanding of cellular excitability and transport mechanisms.
| Molecular weight | 506.20 (free acid basis) |
|---|---|
| Empirical formula | C10H17N6O12P3 · xLi+ · yH2O |
| Assay | ≥93% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble50 mg/mL |
| Storage temperature | −20°C |
| Application | Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate has been used in a study to research the effects of monovalent cations Li+, Na+, K+, NH4+, Rb+ and Cs+ on the solid and solution structures of the nucleic acid components. Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate has also been used in a study to determine that antidepressants inhibit interferon-γ-induced microglial production of IL-6 and nitric oxide. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate used for?
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Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate is used in biochemical research to study cation effects on nucleic acids, cell signaling pathways, neuroscience, and enzyme mechanisms due to its non-hydrolysable ATP analogue properties.
What is the CAS number and molecular formula?
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The CAS number for Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate is 25612-73-1 (free acid). The empirical formula is C10H17N6O12P3 · xLi+ · yH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate with an assay of ≥93% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation. Refer to the safety data sheet for detailed handling instructions and hazard information; the WGK Germany is 3.
How is this product shipped?
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Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate is shipped on dry ice to maintain required storage temperatures.
How can I request a quote or sample?
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Please contact our sales team through the website to request a quotation or inquire about sample availability for Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate.
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