Adenosine 3′-monophosphate
Adenosine 3′-monophosphate (CAS: 84-21-9), with the molecular formula C10H14N5O7P, is a significant metabolite derived from the hydrolysis of 2′,3′-cAMP by phosphodiesterases. This compound plays a role in cellular regulation, notably inhibiting the proliferation of preglomerular vascular smooth muscle and glomerular mesangial cells through A2B receptors. It represents a key component in adenosine-based cell signalling pathways.
- IUPAC
- 3′-AMP,3′-Adenylic acid
- Synonyms
- 3′-AMP3′-Adenylic acid
Cellular Regulation Studies
Adenosine 3′-monophosphate is utilized in research to investigate cellular signalling pathways and regulation mechanisms. Its role in inhibiting cell proliferation via A2B receptors makes it a valuable tool for studying vascular and mesangial cell behaviour.
Biochemical Research
As a metabolite of cyclic AMP, 3′-AMP is important for understanding nucleotide metabolism and signal transduction. It serves as a reference compound or reagent in various biochemical assays and experiments.
Pharmacological Research
Its specific inhibitory action on certain cell types suggests potential applications in understanding and developing treatments for conditions related to abnormal cell growth or vascular function.
| Molecular weight | 347.22 |
|---|---|
| Empirical formula | C10H14N5O7P |
| Storage temperature | −20°C |
| Application | Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Adenosine 3′-monophosphate used for?
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Adenosine 3′-monophosphate (3′-AMP) is used in biochemical and pharmacological research to study cellular regulation, signal transduction, and nucleotide metabolism. It is known to inhibit the proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.
What is the CAS number and formula for Adenosine 3′-monophosphate?
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The CAS number for Adenosine 3′-monophosphate is 84-21-9, and its molecular formula is C10H14N5O7P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Adenosine 3′-monophosphate as a research-grade chemical. The specific assay is not provided in the product data, and TSS does not represent this product as USP, BP, EP, or pharmaceutical grade.
How should Adenosine 3′-monophosphate be handled?
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Handle Adenosine 3′-monophosphate with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at −20°C.
Is Adenosine 3′-monophosphate a controlled substance?
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The provided data does not indicate that Adenosine 3′-monophosphate is a controlled substance.
How is Adenosine 3′-monophosphate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Adenosine 3′-monophosphate, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for Adenosine 3′-monophosphate?
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To request a sample or quote for Adenosine 3′-monophosphate, please contact the Tech Serve Solutions sales team through the website or by phone.
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