Adenosine 5′-(α,β-methylene)diphosphate

CAS 3768-14-7C11H17N5O9P2Biochemicals & Reagents

Adenosine 5′-(α,β-methylene)diphosphate (CAS 3768-14-7), with the empirical formula C11H17N5O9P2 and a molecular weight of 425.23 g/mol, is a nucleotide analog. This compound serves as a specific inhibitor of CD73, an enzyme crucial in regulating adenosinergic signaling pathways. It is primarily utilised in biochemical research to investigate the role of CD73 and related ecto-5′-nucleotidases.

IUPAC: α,β-Methyleneadenosine 5′-diphosphate,ADP[α,β-CH2],AMP-CP
Synonyms: α,β-Methyleneadenosine 5′-diphosphateADP[α,β-CH2]AMP-CP

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Adenosine 5′-(α,β-methylene)diphosphate (C11H17N5O9P2) — chemical structure, CAS 3768-14-7; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsNucleosidesNucleotidesOligonucleotidesNucleotide Analogs

01 /Applications

CD73 Inhibition Studies

Adenosine 5′-(α,β-methylene)diphosphate is employed as a research tool to inhibit the ecto-5′-nucleotidase CD73. This allows for the detailed investigation of adenosinergic signaling pathways and the specific functions of CD73 in cellular processes.

Adenosinergic Signaling Research

This diphosphate analog is used to probe the intricate mechanisms of adenosinergic signaling. By blocking CD73 activity, researchers can elucidate the downstream effects and physiological relevance of this important signaling cascade.

Nucleotide Analog Research

As a synthetic nucleotide analog, AMP-CP is valuable in studies exploring the structural and functional differences between natural nucleotides and their modified counterparts, contributing to a deeper understanding of enzyme-substrate interactions.

02 /Properties

Molecular weight	425.23
Empirical formula	C11H17N5O9P2
Storage temperature	−20°C
Application	Adenosine 5′-(α,β-methylene)diphosphate (AMP-CP) is a CD73 inhibitor and is used to study adenosinergic signaling regulation via CD73/ecto-5′-nucleotidase.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

3768-14-7

MDL number

MFCD00042991

PubChem substance

24896872

Beilstein registry

633678

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Adenosine 5′-(α,β-methylene)diphosphate used for?

Adenosine 5′-(α,β-methylene)diphosphate (AMP-CP) is used in research as a CD73 inhibitor to study adenosinergic signaling regulation via CD73/ecto-5′-nucleotidase.

What is the CAS number and formula for Adenosine 5′-(α,β-methylene)diphosphate?

The CAS number is 3768-14-7, and the empirical formula is C11H17N5O9P2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Adenosine 5′-(α,β-methylene)diphosphate for research purposes. The specific assay and purity are available upon request and are not represented as USP, BP, or EP grade.

What are the safety and handling recommendations?

Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany classification of 3, indicating a high hazard to water.

How is Adenosine 5′-(α,β-methylene)diphosphate shipped and exported?

This product is typically stored at -20°C. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, ensuring appropriate packaging and documentation for international shipments.