5-Methyl-2-pyridinesulfonamide
5-Methyl-2-pyridinesulfonamide (CAS: 65938-77-4), with the molecular formula C6H8N2O2S and a molecular weight of 172.20 g/mol, is a specialised chemical compound. It functions as a key building block in organic synthesis, particularly within heterocyclic chemistry. Its primary documented application is in the development of novel synthetic protocols, such as copper-catalyzed aziridination, making it valuable for research and development in various chemical disciplines.

Development of Synthetic Protocols
5-Methyl-2-pyridinesulfonamide has been utilised in the advancement of catalytic methods. Specifically, it played a role in developing a copper-catalyzed aziridination protocol, demonstrating its utility in creating complex nitrogen-containing heterocycles.
Heterocyclic Chemistry Building Block
As a substituted pyridine derivative, this compound serves as a valuable synthon for constructing more complex heterocyclic structures. Its functional groups allow for diverse chemical transformations, aiding in the synthesis of novel molecular architectures.
Research and Development
This chemical is employed in academic and industrial research settings for exploring new reaction pathways and synthesising target molecules. Its availability supports ongoing investigations in medicinal chemistry and materials science.
| Molecular weight | 172.20 |
|---|---|
| Empirical formula | C6H8N2O2S |
| Assay | ≥97% |
| Application | 5-Methyl-2-pyridinesulfonamide was used to develop a copper-catalyzed aziridination protocol1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methyl-2-pyridinesulfonamide used for?
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5-Methyl-2-pyridinesulfonamide is primarily used as a building block in chemical synthesis, notably in the development of protocols like copper-catalyzed aziridination.
What are the CAS number and molecular formula for 5-Methyl-2-pyridinesulfonamide?
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The CAS number is 65938-77-4, and the molecular formula is C6H8N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methyl-2-pyridinesulfonamide with an assay of ≥97%. We do not represent this product as USP, BP, or EP grade.
How should 5-Methyl-2-pyridinesulfonamide be handled?
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This compound is a potential irritant to the skin, eyes, and respiratory tract. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is 5-Methyl-2-pyridinesulfonamide packed and shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-Methyl-2-pyridinesulfonamide, and can facilitate international orders.
How can I request a quote or sample for 5-Methyl-2-pyridinesulfonamide?
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To request a quote or sample, please use the contact form on our website or contact our sales department directly with your requirements.
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