5-Methyl-2-thienylboronic acid
5-Methyl-2-thienylboronic acid (CAS: 162607-20-7), with the molecular formula C5H7BO2S and a molecular weight of 141.98 g/mol, is a crucial organoboron compound. It serves as a valuable building block in organic synthesis. Primarily utilised as a reactant in Suzuki-Miyaura cross-coupling reactions, this compound facilitates the formation of carbon-carbon bonds, enabling the synthesis of complex molecules in research and development.
- IUPAC
- (5-Methylthien-2-yl)boronic acid,(5-Methylthiophen-2-yl)dihydroxyborane,2-Methylthienyl-5-boronic acid,2-Methylthiophene-5-boronic acid,5-Methyl-2-thiopheneboronic acid
- Synonyms
- 5-Methyl-2-thienylboronic acid(5-Methylthien-2-yl)boronic acid(5-Methylthiophen-2-yl)dihydroxyborane2-Methylthienyl-5-boronic acid2-Methylthiophene-5-boronic acid5-Methyl-2-thiopheneboronic acid

Suzuki-Miyaura Cross-Coupling Reactions
5-Methyl-2-thienylboronic acid is a key reactant for catalysing Suzuki-Miyaura cross-coupling reactions. This application is vital for constructing biaryl and heteroaryl compounds, essential in medicinal chemistry and materials science.
Organic Synthesis Intermediate
As a versatile boronic acid derivative, it functions as an intermediate in various complex organic syntheses. Its structure allows for the introduction of the 5-methyl-2-thienyl moiety into diverse molecular scaffolds.
Heteroaryl Compound Synthesis
This reagent is employed in the synthesis of sophisticated heteroaryl structures. The thienyl group is a common motif in pharmaceuticals and organic electronic materials, making this boronic acid a valuable tool for researchers in these fields.
| Molecular weight | 141.98 |
|---|---|
| Empirical formula | C5H7BO2S |
| Storage temperature | 2-8°C |
| Application | Reactant for:• Suzuki-Miyaura cross-coupling reactions1,2 |
| Melting point | 161.5-166.5 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methyl-2-thienylboronic acid used for?
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5-Methyl-2-thienylboronic acid is primarily used as a reactant in Suzuki-Miyaura cross-coupling reactions for organic synthesis and the creation of complex heteroaryl compounds.
What are the CAS number and chemical formula for 5-Methyl-2-thienylboronic acid?
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The CAS number is 162607-20-7 and the chemical formula is C5H7BO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and grade are available upon request, and it is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for 5-Methyl-2-thienylboronic acid?
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According to GHS classifications, appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. Handle with care in a well-ventilated area.
How is 5-Methyl-2-thienylboronic acid packed, shipped, and exported?
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Tech Serve Solutions ensures secure and compliant packaging for safe transport. We are experienced in exporting chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for 5-Methyl-2-thienylboronic acid?
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To request a sample or quote, please contact our sales team via the website or direct inquiry. Provide your contact details and the product information.
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