5-Methyl-2-pyrrolidinone
5-Methyl-2-pyrrolidinone (CAS: 108-27-0, C5H9NO) is a heterocyclic organic compound with a molecular weight of 99.13 g/mol. It presents as a solid at room temperature. This chemical serves as a versatile building block in organic synthesis, particularly within the pharmaceutical and fine chemical industries. Its structure lends itself to further functionalization, making it a valuable intermediate for creating more complex molecules.

Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of diverse organic compounds. Its pyrrolidinone ring system is a common motif in pharmaceutical agents and other biologically active molecules.
Pharmaceutical Research
Employed in the development of novel drug candidates. The compound's structure can be modified to create libraries of compounds for screening in drug discovery programs.
Fine Chemical Production
Serves as a precursor in the manufacturing of specialised fine chemicals. Its reactive nature allows for incorporation into various synthetic pathways.
| Molecular weight | 99.13 |
|---|---|
| Empirical formula | C5H9NO |
| Assay | 98% |
| Boiling point | 248 °C(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 41-43 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Methyl-2-pyrrolidinone used for?
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5-Methyl-2-pyrrolidinone is primarily used as a versatile building block in organic synthesis, particularly in the development of pharmaceutical agents and fine chemicals.
What are the CAS number and formula for 5-Methyl-2-pyrrolidinone?
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The CAS number for 5-Methyl-2-pyrrolidinone is 108-27-0, and its empirical formula is C5H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Methyl-2-pyrrolidinone with an assay of 98%. This is a technical or research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 5-Methyl-2-pyrrolidinone be handled?
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5-Methyl-2-pyrrolidinone can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Store at 2-8°C.
Is 5-Methyl-2-pyrrolidinone a controlled substance?
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The provided data does not indicate that 5-Methyl-2-pyrrolidinone is a controlled substance.
How is 5-Methyl-2-pyrrolidinone packed and shipped?
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5-Methyl-2-pyrrolidinone is carefully packed for secure handling and export, complying with all relevant shipping regulations for chemical materials.
How can I request a quote or sample for 5-Methyl-2-pyrrolidinone?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our official website or listed contact details, specifying the product name and CAS number.
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