1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione
1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione (CAS 1469-94-9; C15H12O3; molar mass 240.25 g/mol) is an aromatic 1,3-diketone bearing an ortho-hydroxyphenyl group, also known as 2'-hydroxydibenzoylmethane. Supplied as a crystalline solid (melting point 120–122 °C) at 98% assay, it is used principally as a synthetic building block and intermediate, most notably as the classic precursor in flavone and chromone synthesis. Tech Serve Solutions supplies and exports this reagent worldwide.
- Synonyms
- 1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione2'-Hydroxydibenzoylmethaneo-Hydroxydibenzoylmethane1-(2-Hydroxyphenyl)-3-phenylpropane-1,3-dione1,3-Propanedione, 1-(2-hydroxyphenyl)-3-phenyl-HOC6H4COCH2COC6H5
Flavone and chromone synthesis
It is the established precursor to flavone (2-phenyl-4H-chromen-4-one): acid-catalysed intramolecular cyclodehydration of this ortho-hydroxy 1,3-diketone furnishes the chromone ring. The compound is the textbook product of the Baker–Venkataraman rearrangement.
Organic building block
As a reactive β-diketone it serves as a versatile building block for heterocyclic and fine-chemical synthesis, providing a 1,3-dicarbonyl motif for condensation and cyclisation reactions.
Metal chelation and coordination chemistry
Like other β-diketones, it can act as a bidentate chelating ligand and form coordination complexes with metal ions, with the additional ortho-hydroxy group offering a further donor site.
Research and reference reagent
Supplied at 98% assay, it is used in research and method-development laboratories as a synthetic and reference reagent where a defined ortho-hydroxyaryl 1,3-diketone is required.
| Molecular weight | 240.25 |
|---|---|
| Linear formula | HOC6H4COCH2COC6H5 |
| Assay | 98% |
| Melting point | 120-122 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione used for?
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It is used principally as a synthetic intermediate and organic building block. Its best-documented application is as the classic precursor in flavone and chromone synthesis, where acid-catalysed cyclodehydration of this ortho-hydroxy 1,3-diketone forms the chromone ring. As a reactive β-diketone it also features in heterocyclic synthesis and, like related diketones, can act as a chelating ligand for metal ions.
What is the CAS number and molecular formula of 1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione?
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Its CAS number is 1469-94-9 and its molecular formula is C15H12O3 (linear formula HOC6H4COCH2COC6H5), with a molecular weight of 240.25 g/mol. The MDL number is MFCD00043495. It is also known as 2'-hydroxydibenzoylmethane.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a typical assay of 98%, as a technical/research-grade reagent. We do not represent it as a USP, BP or EP pharmacopoeia grade. A Certificate of Analysis and Safety Data Sheet accompany each consignment, and specific assay requirements can be confirmed at the time of enquiry.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with eye protection and gloves, avoid dust formation and inhalation, and ensure adequate ventilation (precautionary statements P261 and P305+P351+P338). It carries German Water Hazard Class (WGK) 3, so release to water should be prevented. Always consult the Safety Data Sheet before use.
How is 1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione packed, shipped and exported?
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The compound is packed as a solid in tightly closed, clearly labelled containers sized to the order, from research quantities to bulk. It is shipped with full documentation, including a Certificate of Analysis and Safety Data Sheet, and exported worldwide in compliance with the applicable transport and customs regulations. Packaging and labelling follow the SDS and destination-country requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the quantity, required assay and your delivery destination, and our team will respond with a quotation, lead time and available pack sizes. Samples can be arranged on request, subject to availability, to support your evaluation and qualification.
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