1-(2-Hydroxyphenyl)-3-phenyl-2-propenone
1-(2-Hydroxyphenyl)-3-phenyl-2-propenone (CAS 1214-47-7), commonly known as 2'-hydroxychalcone, is a crystalline chalcone with the molecular formula C15H12O2 and a molar mass of 224.25 g/mol. This α,β-unsaturated aromatic ketone bears an ortho-hydroxy group on the benzoyl ring, making it a versatile organic building block and a research-grade bioactive small molecule. Tech Serve Solutions supplies it at 98% assay for synthetic chemistry and laboratory research applications worldwide.
- IUPAC
- 2′-Hydroxychalcone,2-Hydroxybenzalacetophenone
- Synonyms
- 2'-Hydroxychalcone2-Hydroxybenzalacetophenone1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one(E)-1-(2-Hydroxyphenyl)-3-phenylprop-2-en-1-one2'-Hydroxy-trans-chalconetrans-2'-Hydroxychalcone
Building block for flavonoid synthesis
The ortho-hydroxy chalcone scaffold is a classic precursor in the preparation of flavones and flavanones via intramolecular oxa-Michael cyclisation. It is widely used in heterocyclic and medicinal chemistry to access oxygen-containing ring systems.
Organic synthesis intermediate
As an α,β-unsaturated ketone (Michael acceptor), it serves as a reactive building block for conjugate additions, condensations and the construction of more complex carbonyl compounds in research-scale synthesis.
Bioactive small molecule for research
Chalcones such as this compound are studied in cell biology and pharmacological research as reference small molecules. Tech Serve Solutions supplies it strictly for laboratory and research use, with no medical or clinical claims.
Reference and analytical standard
With a defined 98% assay and a characteristic melting point of 86-88 °C, the material is suitable as a chemical reference compound and characterised intermediate in method development and structure-activity studies.
| Molecular weight | 224.25 |
|---|---|
| Linear formula | C6H5CH=CHCOC6H4OH |
| Assay | 98% |
| Melting point | 86-88 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... IL1B(3553)rat ... Alox5(25290) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Hydroxyphenyl)-3-phenyl-2-propenone used for?
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It is used mainly as an organic building block and synthetic intermediate. As an ortho-hydroxy chalcone, it is a well-documented precursor to flavones and flavanones and a Michael acceptor in conjugate-addition chemistry. It is also handled as a bioactive small molecule in laboratory and cell-biology research.
What is the CAS number and molecular formula of 1-(2-Hydroxyphenyl)-3-phenyl-2-propenone?
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Its CAS number is 1214-47-7 and its EC number is 214-928-0. The molecular formula is C15H12O2 (linear form C6H5CH=CHCOC6H4OH), with a molecular weight of 224.25 g/mol. The MDL number is MFCD00016441 and the Beilstein registry number is 976324.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum assay of 98% as a research/technical grade material with a melting point of 86-88 °C. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis is provided with each batch, and a specification can be confirmed against your requirement on request.
What are the safety and handling precautions for this chemical?
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It is classified GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Avoid dust formation, use eye protection, gloves and an N95-type dust mask, and follow precautionary advice P261 and P305+P351+P338. It is assigned German water-hazard class WGK 3 (highly hazardous to water), so prevent release to the environment. Always consult the SDS before use.
How is 1-(2-Hydroxyphenyl)-3-phenyl-2-propenone packed, shipped and exported?
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The material is packed in tightly closed, labelled containers appropriate to the order quantity, from laboratory packs to bulk, with full documentation including a certificate of analysis and safety data sheet. As a global supplier and exporter since 1998, Tech Serve Solutions arranges compliant international shipping and export paperwork to suit your destination.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, target specification and delivery destination, and our team will provide a quotation, available pack sizes and lead time. Samples can be discussed for qualified research and commercial enquiries.
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