Cyclopentylboronic acid
Cyclopentylboronic acid (CAS 63076-51-7, C5H11BO2) is a boronic acid derivative with a molecular weight of 113.95 g/mol. It serves as a valuable reagent in organic synthesis, particularly in cross-coupling reactions. This compound is a key building block for constructing more complex molecular architectures in research and development settings.
Cross-Coupling Reactions
Cyclopentylboronic acid is utilised as a reactant in cross-coupling reactions, including those with quinones and aromatic amines. It is also employed in Ruphos-mediated Suzuki cross coupling reactions for the formation of new carbon-carbon bonds.
Arylation and Alkylation
This boronic acid is instrumental in the arylation and alkylation of various organic substrates, such as diphenylisoxazole. Its reactivity facilitates the introduction of cyclopentyl groups or serves as a coupling partner in these transformations.
Organic Synthesis Reagent
As an organometallic reagent, cyclopentylboronic acid is a versatile tool for synthetic chemists. Its applications span the creation of diverse organic molecules used in pharmaceuticals and materials science.
| Molecular weight | 113.95 |
|---|---|
| Empirical formula | C5H11BO2 |
| Assay | ≥95% |
| Application | Reactant involved in:• Cross coupling reactions with quinones1 or aromatic amines2• Arylation and alkylation of diphenylisoxazole3• Ruphos-mediated Suzuki cross coupling reactions4 |
| Melting point | 126 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclopentylboronic acid used for?
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Cyclopentylboronic acid is primarily used as a reactant in various organic synthesis applications, including cross-coupling reactions (e.g., Suzuki coupling), and arylation/alkylation reactions.
What are the CAS number and formula for Cyclopentylboronic acid?
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The CAS number is 63076-51-7 and the empirical formula (Hill notation) is C5H11BO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cyclopentylboronic acid with an assay of ≥95%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling Cyclopentylboronic acid?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany of 3, indicating a high hazard to water.
How is Cyclopentylboronic acid packaged and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details are available upon request, and all shipments comply with international shipping regulations for chemical substances.
How can I request a sample or quote for Cyclopentylboronic acid?
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To request a sample or a quote for Cyclopentylboronic acid, please contact our sales team through the website or direct inquiry channels, providing your specific requirements.
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