1,3-Diethyl-2-thiobarbituric acid
1,3-Diethyl-2-thiobarbituric acid (CAS 5217-47-0) is a heterocyclic organic compound with the molecular formula C8H12N2O2S and a molecular weight of 200.26 g/mol. This pyrimidine derivative is a valuable building block in chemical synthesis. It has found utility as a coinitiator in photopolymerization processes and as a reagent in the synthesis of complex organic molecules, including benzofuro[2,3-d]pyrimidine derivatives.
- Synonyms
- C8H12N2O2S200-26-0
Photopolymerization Coinitiator
1,3-Diethyl-2-thiobarbituric acid serves as a coinitiator in the photopolymerization of dental materials. Its presence facilitates the curing process upon exposure to light.
Synthesis of Heterocyclic Compounds
This compound acts as a reagent in the electrochemical oxidation of specific substrates, enabling the synthesis of benzofuro[2,3-d]pyrimidine derivatives. It is valuable in creating complex heterocyclic structures.
Analytical Reagent
DETBA has been employed in the DETBA assay, a method utilized for the determination of nicotine metabolites in human urine via High-Performance Liquid Chromatography (HPLC).
| Molecular weight | 200.26 |
|---|---|
| Empirical formula | C8H12N2O2S |
| Assay | 99% |
| Solubility | 1 M NaOH: soluble50 mg/mL, clear, colorless to light yellow |
| Application | 1,3-Diethyl-2-thiobarbituric acid (DETBA) was used as coinitiator during the photopolymerization of dental materials1. It was used as reagent in electrochemical oxidation of 3,4-dihydroxybenzoic acid to yield benzofuro[2,3-d]pyrimidine derivatives2. It was used in DETBA assay for determination of nicotine metabolites in human urine by HPLC3. |
| Melting point | 109-112 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-43 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Diethyl-2-thiobarbituric acid used for?
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1,3-Diethyl-2-thiobarbituric acid is used as a coinitiator in photopolymerization, a reagent in synthesizing benzofuro[2,3-d]pyrimidine derivatives, and in analytical assays for determining nicotine metabolites.
What is the CAS number and formula for 1,3-Diethyl-2-thiobarbituric acid?
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The CAS number is 5217-47-0, and the molecular formula is C8H12N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3-Diethyl-2-thiobarbituric acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is classified as acutely toxic if swallowed (H301) and may cause an allergic skin reaction (H317). Handle with appropriate personal protective equipment, including gloves and protective clothing, in a well-ventilated area. Avoid ingestion and skin contact. Refer to the Safety Data Sheet for comprehensive information.
How is 1,3-Diethyl-2-thiobarbituric acid shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We adhere to all relevant regulations for the safe packaging, shipping, and international export of our products, including UN 2811 classification.
How can I request a sample or quote for 1,3-Diethyl-2-thiobarbituric acid?
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Please contact our sales team via the website or provide your requirements through the product inquiry form to request a sample or a formal quotation.
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