1-(2-Isothiocyanatoethyl)-4-methoxybenzene
1-(2-Isothiocyanatoethyl)-4-methoxybenzene (CAS 17427-37-1; molecular formula C10H11NOS; molar mass 193.27 g/mol), also known as 4-methoxyphenethyl isothiocyanate, is an aromatic isothiocyanate organic building block. The reactive isothiocyanate (-N=C=S) group, paired with a para-methoxy-substituted phenethyl backbone, makes it a versatile intermediate for constructing thioureas, thiocarbamates and related sulfur- and nitrogen-containing heterocycles in research and fine-chemical synthesis. Tech Serve Solutions supplies it for laboratory and process applications.
- Synonyms
- 1-(2-Isothiocyanatoethyl)-4-methoxybenzene4-Methoxyphenethyl isothiocyanate2-(4-Methoxyphenyl)ethyl isothiocyanate1-Methoxy-4-(2-isothiocyanatoethyl)benzene4-Methoxyphenethyl isothiocyanate (CAS 17427-37-1)
Thiourea and thiocarbamate synthesis
The isothiocyanate group reacts readily with primary and secondary amines to form substituted thioureas, and with alcohols to give thiocarbamates. This makes the compound a convenient acyl-equivalent for installing a 4-methoxyphenethyl moiety.
Heterocycle construction
Aromatic isothiocyanates such as this are common precursors to nitrogen- and sulfur-containing heterocycles, including thiazoles, thiadiazoles, benzothiazoles and related ring systems used in medicinal-chemistry research.
Pharmaceutical and agrochemical research intermediate
As a difunctional building block bearing both a reactive isothiocyanate and a methoxyaryl group, it serves as an intermediate in the exploratory synthesis of pharmaceutical and agrochemical candidate molecules.
Bioconjugation and labelling chemistry
Isothiocyanates couple with amine groups to form stable thiourea linkages, a reaction widely exploited for tethering, derivatisation and labelling in laboratory studies.
General organic and methodology research
The compound is used as a reference reactant and building block in academic and industrial method-development work where a para-methoxy phenethyl isothiocyanate scaffold is required.
| Molecular weight | 193.27 |
|---|---|
| Empirical formula | C10H11NOS |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Isothiocyanatoethyl)-4-methoxybenzene used for?
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It is used mainly as an organic building block and synthetic intermediate. Its reactive isothiocyanate group couples with amines and alcohols to form thioureas and thiocarbamates, and it serves as a precursor to sulfur- and nitrogen-containing heterocycles in pharmaceutical, agrochemical and general chemistry research.
What is the CAS number and molecular formula of 1-(2-Isothiocyanatoethyl)-4-methoxybenzene?
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The CAS number is 17427-37-1 and the molecular formula is C10H11NOS, with a molecular weight of 193.27 g/mol. It is also commonly known as 4-methoxyphenethyl isothiocyanate.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a technical/research-grade building block for laboratory and process use. Specific assay and purity are confirmed on the certificate of analysis for each lot at the point of enquiry. We do not represent it as a USP, BP or EP pharmacopoeial grade.
How should 1-(2-Isothiocyanatoethyl)-4-methoxybenzene be handled and stored?
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Handle it as a reactive laboratory chemical using appropriate engineering controls and personal protective equipment, including gloves and eye protection, in a well-ventilated area. As an isothiocyanate it is moisture- and amine-sensitive and may be irritating; keep it tightly closed, away from incompatible materials, and refer to the current Safety Data Sheet before use.
How is 1-(2-Isothiocyanatoethyl)-4-methoxybenzene packed, shipped and exported?
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It is packed in suitable laboratory- and bulk-appropriate containers with full labelling and documentation, and exported worldwide in line with applicable transport and customs requirements. Packaging size and configuration are agreed at the time of order.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 17427-37-1 and your required quantity. We will respond with availability, lead time, specification details and a formal quotation, and can arrange a sample where appropriate.
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