1-(2-Hydroxyethyl)pyrrolidine
1-(2-Hydroxyethyl)pyrrolidine is a tertiary amino alcohol (CAS 2955-88-6; formula C6H13NO; molar mass 115.17 g/mol) combining a saturated pyrrolidine ring with a pendant 2-hydroxyethyl group. Supplied as a clear, low-viscosity liquid at around 97% assay, it serves chiefly as a heterocyclic building block and basic intermediate in pharmaceutical and fine-chemical synthesis. Tech Serve Solutions supplies and exports this reagent worldwide to laboratories and manufacturers.
- IUPAC
- 2-Pyrrolidinoethanol,Pyrrolidine-1-ethanol
- Synonyms
- 1-(2-Hydroxyethyl)pyrrolidine2-PyrrolidinoethanolPyrrolidine-1-ethanol1-Pyrrolidineethanol2-(1-Pyrrolidinyl)ethanol2-(Pyrrolidin-1-yl)ethanolN-(2-Hydroxyethyl)pyrrolidine
Pharmaceutical intermediate
Used as a basic amino-alcohol building block in the multi-step synthesis of active pharmaceutical ingredients and candidate molecules. Its pyrrolidine nitrogen and primary hydroxyl group offer two distinct, selective handles for further functionalisation.
Heterocyclic building block
Serves as a C4-to-C8 pyrrolidine scaffold in chemical synthesis programmes, allowing medicinal and process chemists to introduce a saturated nitrogen ring bearing a tethered alcohol.
Reagent for alkylation and derivatisation
The terminal hydroxyl is readily converted to halides, sulfonate esters, ethers or esters, providing a convenient 2-(pyrrolidin-1-yl)ethyl unit for attachment to other molecular frameworks.
Tertiary amine in organic synthesis
As a basic tertiary amine, it can act as an organic base or as a ligand component in laboratory-scale preparations where a soluble, non-nucleophilic-at-nitrogen amine is required.
Research and development
Stocked as a research-grade reagent for method development, structure-activity studies and small-scale process chemistry across academic and industrial laboratories.
| Molecular weight | 115.17 |
|---|---|
| Empirical formula | C6H13NO |
| Assay | 97% |
| Boiling point | 79-81 °C/13 mmHg(lit.) |
| Density | 0.985 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4713 |
Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 56 °C / 132.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Safety statements (S) | 23-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Hydroxyethyl)pyrrolidine used for?
+
It is used mainly as a fine-chemical and pharmaceutical building block. The molecule provides a pyrrolidine ring with a reactive 2-hydroxyethyl side chain, making it a versatile intermediate for alkylation, esterification and the construction of larger nitrogen-containing target molecules in synthesis.
What is the CAS number and molecular formula of 1-(2-Hydroxyethyl)pyrrolidine?
+
The CAS number is 2955-88-6 and the molecular formula is C6H13NO, with a molecular weight of 115.17 g/mol. It is also indexed under EC number 220-976-3, MDL number MFCD00003181 and Beilstein registry 102976.
What grade and purity does Tech Serve Solutions supply?
+
We supply 1-(2-Hydroxyethyl)pyrrolidine as a technical/research-grade reagent at a typical assay of around 97%. We do not represent this product as USP, BP or EP pharmacopoeia grade. A current Certificate of Analysis is provided with each batch on request.
Is 1-(2-Hydroxyethyl)pyrrolidine hazardous, and how should it be handled?
+
Yes. It is classified GHS02 with the signal word Warning and hazard statement H226 (flammable liquid and vapour); the flash point is about 56 °C. Keep it away from heat, sparks and open flames, use it with adequate ventilation, and wear eye protection, gloves and suitable respiratory protection. It carries WGK 3, indicating it is hazardous to water, so prevent release to drains and waterways. Always consult the Safety Data Sheet before use.
How is 1-(2-Hydroxyethyl)pyrrolidine packed, shipped and exported?
+
It is packed in tightly sealed, compatible containers sized to order and labelled to GHS. As a flammable liquid it is classified for transport under UN 1993, Class 3, Packing Group III, and is shipped as dangerous goods in line with applicable ADR, IMDG and IATA rules. Tech Serve Solutions exports worldwide with full documentation.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will provide a quotation, available pack sizes, lead time and a Certificate of Analysis or Safety Data Sheet as needed.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis