N-tert-Butyl-N-(2-methyl-1-phenylpropyl)-O-(1-phenylethyl)hydroxylamine
N-tert-Butyl-N-(2-methyl-1-phenylpropyl)-O-(1-phenylethyl)hydroxylamine (CAS 227000-59-1) is a key alkoxyamine initiator for nitroxide-mediated polymerization (NMP). With a molecular weight of 325.49 g/mol and formula C22H31NO, it is instrumental in the controlled synthesis of styrene and acrylate-based polymers and copolymers, offering precise control over polymer architecture.
- IUPAC
- 2,2,5-Trimethyl-3-(1-phenylethoxy)-4-phenyl-3-azahexane,Alkoxyamine NMP initiator

Nitroxide-Mediated Polymerization (NMP)
This compound serves as a universal alkoxyamine initiator, enabling controlled radical polymerization. It is particularly effective for the synthesis of polymers and copolymers of styrene and acrylates, allowing for fine-tuning of molecular weight and dispersity.
Polymer Science Research
As a specialized reagent, it facilitates advanced polymer synthesis in research settings. Its controlled initiation capabilities are valuable for developing novel polymeric materials with specific properties and architectures.
Materials Science Applications
The controlled polymerization facilitated by this initiator is crucial for developing advanced materials. These materials can find applications in various fields requiring tailored polymer performance.
| Molecular weight | 325.49 |
|---|---|
| Empirical formula | C22H31NO |
| Density | 0.968 g/mL at 25 °C |
| Refractive index | n20/D 1.536 |
| Storage temperature | −20°C |
| Application | Universal alkoxyamine initiator for nitroxide-mediated living radical polymerization (NMP initiator). Particularly useful for synthesis of styrene and acrylate polymers and co-polymers.1 |


Hazard statements
- H272May intensify fire; oxidiser
- H400Very toxic to aquatic life
Precautionary statements
- P220Keep away from clothing and combustible materials
- P273Avoid release to the environment
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3139 5.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | O,N |
| Risk statements (R) | 8-50/53 |
| Safety statements (S) | 17-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-tert-Butyl-N-(2-methyl-1-phenylpropyl)-O-(1-phenylethyl)hydroxylamine used for?
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It is used as a universal alkoxyamine initiator for nitroxide-mediated living radical polymerization (NMP), particularly effective for styrene and acrylate polymers and copolymers.
What is the CAS number and molecular formula?
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The CAS number is 227000-59-1, and the molecular formula is C22H31NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and technical applications. The exact grade and purity are available upon request; we do not represent this product as USP, BP, or EP grade.
How should this chemical be handled safely?
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This compound is an oxidizer (H272) and very toxic to aquatic life with long-lasting effects (H400). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., N100 or P3 cartridges), and store away from combustible materials. Avoid release to the environment.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. Please contact us for export details and quotations.
How can I request a sample or quote?
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Please contact the Tech Serve Solutions sales team directly to request a sample or a quotation for this product.
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