5-Fluoroorotic acid hydrate
5-Fluoroorotic acid hydrate (CAS: 207291-81-4) is a pyrimidine derivative with the empirical formula C5H3FN2O4 · xH2O. This compound, with an anhydrous molecular weight of 174.09, serves as a valuable building block in chemical synthesis. Its primary documented application is in the selection of orotidine-5′-phosphate decarboxylase mutants of *Saccharomyces cerevisiae*, making it a useful reagent in molecular biology and biochemical research.
- IUPAC
- 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid,5-Fluorouracil-4-carboxylic acid
- Synonyms
- 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid5-Fluorouracil-4-carboxylic acid
Biochemical Research Reagent
5-Fluoroorotic acid hydrate is employed in biochemical studies, particularly for the selection of specific yeast mutants. It aids in identifying strains with altered orotidine-5′-phosphate decarboxylase activity.
Genetic Selection Tool
This compound acts as a selection agent in molecular biology. It is used to isolate mutants of *Saccharomyces cerevisiae* that exhibit resistance or altered pathways related to orotidine-5′-phosphate metabolism.
Synthetic Intermediate
As a fluorinated pyrimidine derivative, it functions as a building block in organic synthesis, potentially for the creation of novel heterocyclic compounds with pharmaceutical or biological relevance.
| Molecular weight | 174.09 (anhydrous basis) |
|---|---|
| Empirical formula | C5H3FN2O4 · xH2O |
| Assay | 98% |
| Storage temperature | −20°C |
| Application | Useful in the selection of orotidine-5′-phosphate decarboxylase mutants of Saccharomyces cerevisiae. |
| Melting point | 278 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoroorotic acid hydrate primarily used for?
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5-Fluoroorotic acid hydrate is primarily used as a reagent in biochemical research for the selection of orotidine-5′-phosphate decarboxylase mutants of *Saccharomyces cerevisiae*.
What are the CAS number and chemical formula for 5-Fluoroorotic acid hydrate?
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The CAS number is 207291-81-4, and the empirical formula is C5H3FN2O4 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoroorotic acid hydrate with an assay of 98%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should 5-Fluoroorotic acid hydrate be handled safely?
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5-Fluoroorotic acid hydrate is classified as harmful if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves, in a well-ventilated area.
How is this chemical shipped and exported?
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As a specialist global supplier, Tech Serve Solutions exports fine chemicals worldwide, adhering to all relevant shipping and customs regulations for hazardous materials.
How can I request a sample or obtain a quote for 5-Fluoroorotic acid hydrate?
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To request a sample or obtain a quotation, please contact our sales department via the website or direct email, providing your required quantity and shipping details.
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