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5-Fluorosalicylic acid

CAS 345-16-4FC6H3-2-(OH)CO2HChemical Synthesis

5-Fluorosalicylic acid (CAS: 345-16-4, Formula: FC6H3-2-(OH)CO2H) is a fluorinated organic compound with a molecular weight of 156.11 g/mol. This light brown, crystalline solid serves as a valuable building block in organic synthesis. Its structure, featuring both a hydroxyl and a carboxylic acid group alongside a fluorine atom on the aromatic ring, makes it a versatile intermediate for the development of novel molecules in pharmaceuticals and materials science.

IUPAC
5-Fluoro-2-hydroxybenzoic acid
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5-Fluorosalicylic acid (FC6H3-2-(OH)CO2H) — chemical structure, CAS 345-16-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksCarbonyl CompoundsCarboxylic AcidsChemical SynthesisFluorinated Building BlocksOrganic Building Blocks
01 /Applications

Pharmaceutical Intermediate

Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, leveraging its fluorinated aromatic structure for targeted biological activity.

Organic Synthesis Building Block

Serves as a key precursor in multi-step syntheses, enabling the introduction of a fluorinated salicylic acid moiety into complex organic structures.

Material Science Research

Employed in the development of new materials where the incorporation of fluorine can modify properties such as thermal stability or hydrophobicity.

02 /Properties
Molecular weight156.11
Linear formulaFC6H3-2-(OH)CO2H
Assay97%
Gradepurum
Colourlight brown
Melting point177-179 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
345-16-4
MDL number
MFCD00002456
PubChem substance
24871054
Beilstein registry
2209120
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Fluorosalicylic acid used for?

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5-Fluorosalicylic acid is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates and novel materials where a fluorinated salicylic acid structure is desired.

What is the CAS number and chemical formula for 5-Fluorosalicylic acid?

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The CAS number for 5-Fluorosalicylic acid is 345-16-4, and its chemical formula is FC6H3-2-(OH)CO2H.

What grade and purity does Tech Serve Solutions supply for 5-Fluorosalicylic acid?

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Tech Serve Solutions supplies 5-Fluorosalicylic acid with a minimum purity of 97% (purum grade). We do not represent this product as USP, BP, or EP grade.

How should 5-Fluorosalicylic acid be handled safely?

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5-Fluorosalicylic acid is classified as an irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling information.

Can Tech Serve Solutions export 5-Fluorosalicylic acid?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-Fluorosalicylic acid, serving customers worldwide.

How can I request a quote or sample of 5-Fluorosalicylic acid?

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To request a quote or a sample of 5-Fluorosalicylic acid, please contact our sales team via the website or direct email, providing your specific requirements.

Need 5-Fluorosalicylic acid in a specific grade or volume?