5-Fluoroisatin
5-Fluoroisatin (CAS 443-69-6) is a fluorinated heterocyclic building block with the molecular formula C8H4FNO2 and a molecular weight of 165.12 g/mol. This compound serves as a key reactant in the synthesis of various complex organic molecules. Its applications span the development of potential pharmaceuticals, including antimycobacterial agents and kinase inhibitors, as well as biologically relevant synthesis scaffolds.
- IUPAC
- 5-Fluoro-2,3-indoledione,NSC 39161
Synthesis of Spiro[indole-thiazolidinones]
5-Fluoroisatin is employed as a precursor in the preparation of spiro[indole-thiazolidinones], which are recognised as biologically relevant synthesis scaffolds.
Development of Antimycobacterial Agents
This compound is utilised as a reactant in the synthesis pathways leading to novel potential antimycobacterial agents.
Kinase Inhibitor Research
5-Fluoroisatin serves as a building block for the creation of inhibitors targeting kinases such as c-Met and TAK1, which are important in cellular signalling pathways.
Antiviral Compound Synthesis
The molecule is a valuable intermediate for synthesising compounds with potential activity against viruses, such as herpes simplex virus.
| Molecular weight | 165.12 |
|---|---|
| Empirical formula | C8H4FNO2 |
| Assay | 98% |
| Application | Reactant for preparation of:• Spiro[indole-thiazolidinones] as biologically relevan synthesis scaffolds1• Potential antimycobacterial agents2• Inhibitors of c-Met kinase3• Inhibitors of TAK1 kinase4• Herpes simplex virus inhibitors5• IKK |
| Melting point | 224-227 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoroisatin used for?
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5-Fluoroisatin is primarily used as a reactant in chemical synthesis for developing potential pharmaceuticals, including antimycobacterial agents, kinase inhibitors, and antiviral compounds, as well as biologically relevant synthesis scaffolds.
What are the CAS number and formula for 5-Fluoroisatin?
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The CAS number for 5-Fluoroisatin is 443-69-6, and its empirical formula is C8H4FNO2.
What grade and purity does Tech Serve Solutions supply for 5-Fluoroisatin?
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Tech Serve Solutions supplies 5-Fluoroisatin with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 5-Fluoroisatin be handled safely?
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5-Fluoroisatin is classified with a Warning signal word and has hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask type N95 (US). Ensure adequate ventilation.
Is 5-Fluoroisatin exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Fluoroisatin.
How can I request a sample or quote for 5-Fluoroisatin?
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To request a sample or a quote for 5-Fluoroisatin, please contact our sales department through the website or by phone.
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