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5-Fluoropyridine-3-carboxylic acid

CAS 402-66-4C6H4FNO2Chemical Synthesis

5-Fluoropyridine-3-carboxylic acid (CAS: 402-66-4), with the molecular formula C6H4FNO2 and a molecular weight of 141.10 g/mol, is a specialised fluorinated heterocyclic building block. It is a valuable intermediate in organic synthesis, particularly for the introduction of a fluoropyridine moiety into more complex molecules. Its utility spans research and development, contributing to the synthesis of novel compounds in various chemical disciplines.

IUPAC
5-Fluoronicotinic acid
Synonyms
5-Fluoronicotinic acid
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5-Fluoropyridine-3-carboxylic acid (C6H4FNO2) — chemical structure, CAS 402-66-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisFluorinated Building BlocksHalogenated HeterocyclesHeterocyclic Building BlocksPyridines More...
01 /Applications

Fluorinated Heterocycle Synthesis

This compound serves as a key intermediate for constructing fluorinated heterocyclic structures. The presence of both a pyridine ring and a fluorine atom offers unique electronic and steric properties for targeted molecular design in medicinal chemistry and materials science.

Pharmaceutical Intermediate

5-Fluoropyridine-3-carboxylic acid is employed in the synthesis pathways of potential pharmaceutical agents. Its structural features can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.

Agrochemical Research

The compound may be utilised in the development of novel agrochemicals. Fluorinated organic molecules often exhibit enhanced biological activity and metabolic stability, making them attractive targets for crop protection agents.

Materials Science

It can be incorporated into functional materials where the fluoropyridine unit imparts specific electronic or optical characteristics. This is relevant for research into advanced polymers or organic electronics.

02 /Properties
Molecular weight141.10
Empirical formulaC6H4FNO2
Melting point193-198 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
402-66-4
MDL number
MFCD01318537
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Fluoropyridine-3-carboxylic acid used for?

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5-Fluoropyridine-3-carboxylic acid is used as a building block in organic synthesis, particularly for creating fluorinated heterocyclic compounds. It finds applications in pharmaceutical research, agrochemical development, and materials science due to its unique structural features.

What are the CAS number and molecular formula for 5-Fluoropyridine-3-carboxylic acid?

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The CAS number for 5-Fluoropyridine-3-carboxylic acid is 402-66-4, and its molecular formula is C6H4FNO2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 5-Fluoropyridine-3-carboxylic acid typically at a research or technical grade. The exact purity is specified on the Certificate of Analysis provided with each batch. We do not represent this product as USP, BP, EP or other pharmacopoeia grades unless explicitly stated.

How should 5-Fluoropyridine-3-carboxylic acid be handled safely?

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5-Fluoropyridine-3-carboxylic acid is classified with GHS07 and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves and eye protection, and ensure adequate ventilation. Avoid breathing dust.

Can Tech Serve Solutions export 5-Fluoropyridine-3-carboxylic acid internationally?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, including 5-Fluoropyridine-3-carboxylic acid, to researchers and industries worldwide.

How can I request a quote or sample of 5-Fluoropyridine-3-carboxylic acid?

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To request a quote or a sample of 5-Fluoropyridine-3-carboxylic acid, please use the contact form on our website or contact our sales department directly. Please specify the quantity required and your shipping destination.

Need 5-Fluoropyridine-3-carboxylic acid in a specific grade or volume?