5-Fluorouracil

CAS 51-21-8C4H3FN2O2Chemical Synthesis

5-Fluorouracil (CAS 51-21-8), with the molecular formula C4H3FN2O2 and a molecular weight of 130.08 g/mol, is a pyrimidine analogue with significant applications in chemical synthesis. It functions as an inhibitor of DNA synthesis. Available from Tech Serve Solutions with a purity of 99%, this compound is supplied for research and development purposes.

IUPAC: 2,4-Dihydroxy-5-fluoropyrimidine,5-FU,5-Fluoro-2,4(1H,3H)-pyrimidinedione
Synonyms: 2,4-Dihydroxy-5-fluoropyrimidine5-FU5-Fluoro-2,4(1H,3H)-pyrimidinedione

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5-Fluorouracil (C4H3FN2O2) — chemical structure, CAS 51-21-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC4 to C5Chemical SynthesisHeterocyclic Building BlocksPyrimidines

01 /Applications

DNA Synthesis Inhibition

5-Fluorouracil is recognised for its role as an inhibitor of DNA synthesis. This property underpins its utility in various chemical research applications.

Chemical Synthesis Intermediate

As a heterocyclic building block, 5-Fluorouracil serves as a valuable intermediate in complex organic synthesis pathways. Its pyrimidine structure makes it useful for creating diverse molecular architectures.

Research and Development

This compound is frequently utilised in laboratory settings for scientific investigation and the development of new chemical entities. Its specific biological activity makes it a subject of interest in biochemical research.

02 /Properties

Molecular weight	130.08
Empirical formula	C4H3FN2O2
Assay	99%
Solubility	1 M NH4OH: solubleDMSO/DMF: solublemethanol: soluble
Application	Inhibitor of DNA synthesis.1,2
Melting point	282-286 °C (dec.)(lit.)

03 /Safety & handling

Precautionary statements

P273Avoid release to the environment
P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1/PG 3
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

51-21-8

MDL number

MFCD00006018

PubChem substance

24888466

Beilstein registry

127172

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Fluorouracil primarily used for?

5-Fluorouracil (CAS 51-21-8) is primarily used as an inhibitor of DNA synthesis in chemical research and as a building block in chemical synthesis.

What are the CAS number and molecular formula for 5-Fluorouracil?

The CAS number for 5-Fluorouracil is 51-21-8, and its molecular formula is C4H3FN2O2.

What grade and purity does Tech Serve Solutions supply for 5-Fluorouracil?

Tech Serve Solutions supplies 5-Fluorouracil with an assay of 99%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.

How should 5-Fluorouracil be handled safely?

5-Fluorouracil is classified as harmful if swallowed (Risk Statement 22) and is labelled with hazard code Xn. Handle with appropriate personal protective equipment and follow precautionary statements P273 (Avoid release to the environment) and P301 + P310 (IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician).

Can I request a sample or quote for 5-Fluorouracil?

Yes, to request a sample or a quote for 5-Fluorouracil, please contact our sales team through the website or by phone. Details are available on the 'Contact Us' page.

How is 5-Fluorouracil packed and shipped?

5-Fluorouracil is packed according to standard chemical handling procedures and shipped internationally by Tech Serve Solutions in compliance with all relevant transport regulations, including UN 2811 (6.1/PG 3).