5-Formyl-2-furanylboronic acid
5-Formyl-2-furanylboronic acid (CAS: 27329-70-0; Formula: C5H5BO4; Molar Mass: 139.90) is a versatile organic compound featuring both an aldehyde and a boronic acid functional group. This unique structure makes it a valuable building block in organic synthesis. It is primarily employed as a reactant in Suzuki coupling reactions and in the synthesis of complex molecules with potential biological activities.
- IUPAC
- 5-Formyl-2-furanboronic acid
Suzuki Coupling Reactions
5-Formyl-2-furanylboronic acid serves as a key reactant in Suzuki-Miyaura cross-coupling reactions. This application is particularly noted in the synthesis of novel materials for stable dye-sensitized solar cells.
Synthesis of Biologically Active Molecules
This boronic acid is utilized in the preparation of various biologically significant compounds. Its reactivity facilitates the synthesis of molecules like HIF-1 inhibitors and disalicylic acid-furanyl derivatives with potential therapeutic applications.
Pharmaceutical Intermediate
The compound acts as a crucial intermediate in the development of pharmaceutical agents. It has been employed in the synthesis pathways for HIV-1 integrase inhibitors and epidermal growth factor receptor inhibitors.
| Molecular weight | 139.90 |
|---|---|
| Empirical formula | C5H5BO4 |
| Application | Reactant involved in Suzuki coupling for synthesis of stable dye-senstitized solar cells1,2,3Reactant involved in synthesis of biologically active molecules including:• Heteroarylation for the synthesis of HIF-1 inhibitors4• Disalicylic acid-furanyl derivatives to inhibit ephrin binding5 • HIV-1 integrase inhibitors6• Epidermal growth factor receptor inhibitors7 |
| Melting point | 136 °C (dec.)(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Formyl-2-furanylboronic acid used for?
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5-Formyl-2-furanylboronic acid is primarily used as a reactant in Suzuki coupling reactions, particularly for the synthesis of dye-sensitized solar cells, and in the synthesis of various biologically active molecules including HIF-1 inhibitors, disalicylic acid-furanyl derivatives, HIV-1 integrase inhibitors, and epidermal growth factor receptor inhibitors.
What are the CAS number and formula for 5-Formyl-2-furanylboronic acid?
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The CAS number for 5-Formyl-2-furanylboronic acid is 27329-70-0, and its chemical formula is C5H5BO4.
What grade and purity does Tech Serve Solutions supply for 5-Formyl-2-furanylboronic acid?
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Tech Serve Solutions supplies 5-Formyl-2-furanylboronic acid. The specific assay and grade available are detailed on our product specification sheet. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
What are the safety and handling considerations for 5-Formyl-2-furanylboronic acid?
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5-Formyl-2-furanylboronic acid is classified with GHS symbol GHS05 and the signal word Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, and protective gloves, must be worn. Ensure adequate ventilation and follow P280-P305 + P351 + P338-P310 precautionary statements.
How is 5-Formyl-2-furanylboronic acid packed, shipped, and exported?
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Tech Serve Solutions professionally packs and ships fine chemicals globally, adhering to all relevant transport regulations, including UN 3261 8 / PGIII for this product.
How can I request a sample or quote for 5-Formyl-2-furanylboronic acid?
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To request a sample or a quote for 5-Formyl-2-furanylboronic acid, please use the contact form on our website or call our sales team directly.
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