5-Formyl-2-thienylboronic acid
5-Formyl-2-thienylboronic acid (CAS 4347-33-5), with the molecular formula C5H5BO3S and a molecular weight of 155.97 g/mol, is a key organic building block. This thiophene derivative features both a boronic acid moiety and an aldehyde group, making it a versatile reagent in organic synthesis. It is primarily employed in cross-coupling reactions and as an intermediate for the synthesis of pharmaceuticals and advanced materials.
- IUPAC
- 5-Formyl-2-thiopheneboronic acid
Suzuki-Miyaura Coupling Reagent
Utilised as a coupling partner in Suzuki-Miyaura reactions for the formation of carbon-carbon bonds, enabling the synthesis of complex biaryl and heteroaryl compounds.
Pharmaceutical Intermediate
Serves as a crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
Materials Science
Incorporated in the development of novel organic materials, including conjugated polymers and organic electronic components.
Organic Synthesis
A versatile reagent for introducing the 5-formyl-2-thienyl motif into various organic structures via reactions involving its boronic acid functionality.
| Molecular weight | 155.97 |
|---|---|
| Empirical formula | C5H5BO3S |
| Assay | ≥95.0% |
| Melting point | 132-135 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Formyl-2-thienylboronic acid used for?
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5-Formyl-2-thienylboronic acid is predominantly used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is also a key intermediate in the development of pharmaceuticals and advanced materials.
What is the CAS number and formula for 5-Formyl-2-thienylboronic acid?
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The CAS number for 5-Formyl-2-thienylboronic acid is 4347-33-5 and its formula is C5H5BO3S.
What grade and purity does Tech Serve Solutions supply for 5-Formyl-2-thienylboronic acid?
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Tech Serve Solutions supplies 5-Formyl-2-thienylboronic acid with a purity of ≥95.0%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling 5-Formyl-2-thienylboronic acid?
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When handling 5-Formyl-2-thienylboronic acid, ensure adequate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance has a WGK rating of 3 in Germany, indicating it is hazardous to water.
How is 5-Formyl-2-thienylboronic acid packed, shipped, and exported?
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Tech Serve Solutions, a global supplier, packs, ships, and exports chemicals in compliance with international regulations. Specific packaging details are available upon request.
How can I request a quote or sample of 5-Formyl-2-thienylboronic acid?
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To request a quote or sample of 5-Formyl-2-thienylboronic acid, please contact our sales team through the TSS website or directly via email/phone.
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