5-Chloro-2-fluorobenzenesulfonyl chloride
5-Chloro-2-fluorobenzenesulfonyl chloride (CAS: 351003-49-1), with the molecular formula ClC6H3(F)SO2Cl and a molecular weight of 229.06 g/mol, is a reactive aryl fluorinated building block. It is characterised by the presence of both a sulfonyl chloride group and fluorine and chlorine substituents on the benzene ring, making it a valuable intermediate in organic synthesis. This compound is primarily employed in the development of novel chemical entities and materials.
Synthesis of Organic Intermediates
This sulfonyl chloride serves as a key intermediate in the synthesis of more complex organic molecules. Its reactive sulfonyl chloride moiety readily participates in nucleophilic substitution reactions, enabling the introduction of the 5-chloro-2-fluorobenzenesulfonyl group into various substrates.
Pharmaceutical Research and Development
The compound is utilised as a building block in the research and development of new pharmaceutical agents. The specific arrangement of halogens and the sulfonyl group can impart unique properties to potential drug candidates.
Material Science Applications
5-Chloro-2-fluorobenzenesulfonyl chloride can be employed in the synthesis of novel materials where its structural features contribute to desired material properties, such as thermal stability or specific electronic characteristics.
| Molecular weight | 229.06 |
|---|---|
| Linear formula | ClC6H3(F)SO2Cl |
| Assay | 97% |
| Melting point | 41-44 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 22-26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-fluorobenzenesulfonyl chloride used for?
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5-Chloro-2-fluorobenzenesulfonyl chloride is used as a building block in organic synthesis, particularly in pharmaceutical research and the development of novel materials.
What are the CAS number and formula for this compound?
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The CAS number is 351003-49-1 and the linear formula is ClC6H3(F)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Chloro-2-fluorobenzenesulfonyl chloride be handled?
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This compound is classified as Danger and carries H314 hazard statements, indicating it causes severe skin burns and eye damage. It also reacts violently with water. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, must be worn. Handle in a well-ventilated area and avoid contact with water.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Chloro-2-fluorobenzenesulfonyl chloride.
How can I request a sample or quote?
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Please contact our sales team via the website or by telephone to request a sample or a quotation for 5-Chloro-2-fluorobenzenesulfonyl chloride.
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