5-Chloro-2-fluorobenzoyl chloride
5-Chloro-2-fluorobenzoyl chloride (CAS: 394-29-6) is a crucial aryl fluorinated building block with the linear formula ClC<sub>6</sub>H<sub>3</sub>(F)COCl and a molecular weight of 193.00 g/mol. This reactive acid halide serves as a versatile intermediate in organic synthesis. It is primarily employed in the development of complex organic molecules and specialised chemical compounds, contributing to advancements in material science and chemical research.
Organic Synthesis Intermediate
Utilised as a key building block in the multi-step synthesis of various organic compounds. Its reactive acyl chloride group readily participates in acylation reactions, enabling the formation of ester, amide, and ketone linkages.
Pharmaceutical Research
Serves as a precursor in the synthesis of novel pharmaceutical agents and drug candidates. The incorporation of the chloro-fluoro-benzoyl moiety can impart specific physicochemical properties to the target molecules.
Agrochemical Development
Employed in the research and development of new agrochemicals, such as pesticides and herbicides. It contributes to the structural diversity of active ingredients.
Material Science
Can be used in the synthesis of specialised polymers and functional materials where the unique electronic and structural properties of the fluorinated aromatic ring are desired.
| Molecular weight | 193.00 |
|---|---|
| Linear formula | ClC6H3(F)COCl |
| Assay | 97% |
| Boiling point | 217-218 °C(lit.) |
| Density | 1.459 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5545(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 100 °C / 212 °F |
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-fluorobenzoyl chloride used for?
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5-Chloro-2-fluorobenzoyl chloride is primarily used as a reactive intermediate and building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialised materials.
What is the CAS number and molecular formula for 5-Chloro-2-fluorobenzoyl chloride?
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The CAS number is 394-29-6, and its linear molecular formula is ClC<sub>6</sub>H<sub>3</sub>(F)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-2-fluorobenzoyl chloride with an assay of 97%. This is typically a technical or research grade; TSS does not represent it as USP, BP, or EP grade.
How should 5-Chloro-2-fluorobenzoyl chloride be handled safely?
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This compound is dangerous and causes severe skin burns and eye damage (H314). Handle with extreme caution, wearing appropriate personal protective equipment including a face shield, gloves, goggles, and suitable respiratory protection (e.g., type ABEK respirator filter). In case of contact, immediately flush with plenty of water and seek medical attention.
Is 5-Chloro-2-fluorobenzoyl chloride a controlled substance?
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The provided data does not indicate that 5-Chloro-2-fluorobenzoyl chloride is a controlled substance.
How is 5-Chloro-2-fluorobenzoyl chloride packed, shipped, and exported?
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5-Chloro-2-fluorobenzoyl chloride is typically packed and shipped according to UN 3265, Class 8, Packing Group III regulations. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a sample or a quote for 5-Chloro-2-fluorobenzoyl chloride?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by calling our direct line.
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