5-Chloro-2-fluoro-3-methylphenylboronic acid
5-Chloro-2-fluoro-3-methylphenylboronic acid (CAS: 352535-87-6) is a specialised aryl boronic acid derivative. With a molecular weight of 188.39 g/mol and empirical formula C7H7BClFO2, it serves as a valuable building block in organic synthesis. This compound is particularly useful in cross-coupling reactions, facilitating the introduction of substituted phenyl moieties into complex molecules across various chemical research and development sectors.
Suzuki-Miyaura Coupling Reagent
This compound functions as a key coupling partner in Suzuki-Miyaura reactions. It enables the formation of carbon-carbon bonds, allowing for the synthesis of biaryl compounds and other complex organic structures used in medicinal chemistry and materials science.
Intermediate in Pharmaceutical Synthesis
As a functionalised aryl boronic acid, it is employed as an intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific substitution pattern can be crucial for achieving desired biological activity in drug candidates.
Building Block for Organic Materials
The compound can be utilised in the development of novel organic materials, such as those for organic light-emitting diodes (OLEDs) or advanced polymers. Its structure allows for the precise tailoring of electronic and optical properties.
Research and Development
This boronic acid is a valuable reagent for synthetic chemists in academic and industrial research laboratories exploring new synthetic methodologies and novel compound discovery.
| Molecular weight | 188.39 |
|---|---|
| Empirical formula | C7H7BClFO2 |
| Melting point | 272-277 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-fluoro-3-methylphenylboronic acid used for?
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5-Chloro-2-fluoro-3-methylphenylboronic acid is primarily used as a reagent in Suzuki-Miyaura coupling reactions, an intermediate in pharmaceutical synthesis, and a building block for organic materials and general chemical research and development.
What is the CAS number and formula for 5-Chloro-2-fluoro-3-methylphenylboronic acid?
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The CAS number is 352535-87-6 and the empirical formula is C7H7BClFO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade chemical. The specific assay or purity is determined by the product batch and available upon request or on the Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Refer to the Safety Data Sheet (SDS) for comprehensive handling and hazard information. It is classified as WGK 2 in Germany.
How is 5-Chloro-2-fluoro-3-methylphenylboronic acid shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals. This product is carefully packed and shipped in compliance with international regulations for chemical transport.
How can I request a sample or a quote?
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To request a sample or a quote for 5-Chloro-2-fluoro-3-methylphenylboronic acid, please contact our sales team through the TSS website or via the provided contact details.
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