5-Chloro-2-(trifluoromethyl)pyridine
5-Chloro-2-(trifluoromethyl)pyridine (CAS: 349-94-0; Formula: C6H3ClF3N; Molar Mass: 181.54 g/mol) is a halogenated heterocyclic compound supplied by Tech Serve Solutions. It is a key building block in organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. Its unique structure, featuring both a pyridine ring and a trifluoromethyl group, offers valuable reactivity for creating complex molecular architectures. Available at 97% purity, it is suitable for research and development purposes.

Pharmaceutical Intermediates
Used as a foundational component in the synthesis of active pharmaceutical ingredients (APIs), enabling the creation of new therapeutic agents. Its halogenated pyridine structure is often incorporated into molecules targeting various biological pathways.
Agrochemical Synthesis
Serves as a versatile intermediate for the development of advanced pesticides, herbicides, and fungicides. The trifluoromethyl and chlorine substituents can enhance the efficacy and stability of agricultural chemicals.
Material Science
Investigated for potential applications in the development of functional materials, leveraging its electronic and structural properties. It can be a precursor for specialised polymers or organic electronic components.
Organic Synthesis Reagent
A valuable reagent in academic and industrial research labs for exploring new synthetic methodologies and creating novel organic compounds. Its reactivity allows for diverse functionalisation strategies.
| Molecular weight | 181.54 |
|---|---|
| Empirical formula | C6H3ClF3N |
| Assay | 97% |
| Melting point | 35-37 °C |


Hazard statements
- H228Flammable solid
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 54 °C / 129.2 °F |
|---|---|
| Transport (UN / ADR) | UN 2926 4.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-(trifluoromethyl)pyridine used for?
+
5-Chloro-2-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also employed in material science research.
What are the CAS number and formula for 5-Chloro-2-(trifluoromethyl)pyridine?
+
The CAS number is 349-94-0 and the empirical formula is C6H3ClF3N.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 5-Chloro-2-(trifluoromethyl)pyridine with an assay of 97%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade unless explicitly stated.
What are the main hazards associated with 5-Chloro-2-(trifluoromethyl)pyridine?
+
This compound is flammable (H228) and harmful if swallowed (H301). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
How is 5-Chloro-2-(trifluoromethyl)pyridine packed, shipped, and exported?
+
Products are carefully packed according to international shipping regulations and are exported globally by Tech Serve Solutions. Specific packaging details can be provided upon request.
How can I request a sample or quote for 5-Chloro-2-(trifluoromethyl)pyridine?
+
Please contact our sales team via the website or provide your details to receive a prompt response regarding samples or quotes.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis