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5-Chloro-2-ethoxyphenylboronic acid

CAS 352534-86-2C6H3ClOCH2CH3B(OH)2Chemical Synthesis

5-Chloro-2-ethoxyphenylboronic acid (CAS: 352534-86-2) is an organoboron compound with the linear formula C8H10BClO3 and a molecular weight of 200.43 g/mol. As a disubstituted aryl boronic acid, it serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure makes it suitable for introducing specific phenyl moieties into more complex molecules, finding utility in the research and development sectors of pharmaceuticals and materials science.

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5-Chloro-2-ethoxyphenylboronic acid (C6H3ClOCH2CH3B(OH)2) — chemical structure, CAS 352534-86-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Aryl Boronic AcidsBoronic AcidsChemical Synthesis
01 /Applications

Suzuki-Miyaura Cross-Coupling Reagent

This boronic acid is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. It facilitates the synthesis of biaryl compounds and other complex organic structures.

Intermediate in Organic Synthesis

Utilised as a versatile intermediate for the construction of diverse organic molecules. Its chloro and ethoxy substituents offer specific reactivity points for further chemical modifications.

Pharmaceutical Research and Development

Contributes to the synthesis of potential drug candidates and active pharmaceutical ingredients (APIs). Its unique structural features are valuable in medicinal chemistry programmes.

Materials Science Applications

Can be employed in the development of novel organic materials, such as polymers or functionalised surfaces, where precise structural control is required.

02 /Properties
Molecular weight200.43
Linear formulaC6H3ClOCH2CH3B(OH)2
Melting point120-124 °C(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
352534-86-2
MDL number
MFCD03427055
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Chloro-2-ethoxyphenylboronic acid used for?

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5-Chloro-2-ethoxyphenylboronic acid is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions and as a versatile intermediate in organic synthesis for pharmaceuticals and materials science.

What is the CAS number and formula for this compound?

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The CAS number for 5-Chloro-2-ethoxyphenylboronic acid is 352534-86-2, and its linear formula is C8H10BClO3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 5-Chloro-2-ethoxyphenylboronic acid typically as a research or technical grade. The precise assay and purity are detailed in the product's specification sheet; TSS does not represent this product as USP, BP, or EP grade.

What are the safety and handling considerations for 5-Chloro-2-ethoxyphenylboronic acid?

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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive handling and hazard information.

How is 5-Chloro-2-ethoxyphenylboronic acid packed and shipped?

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This chemical is carefully packed to ensure integrity during transit and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.

How can I request a quote or sample?

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To request a quote or sample of 5-Chloro-2-ethoxyphenylboronic acid, please contact our sales team through the website or by phone, providing your specific requirements.

Need 5-Chloro-2-ethoxyphenylboronic acid in a specific grade or volume?