5-Chloro-2-fluoroaniline

CAS 2106-05-0ClC6H3(F)NH2Chemical Synthesis

5-Chloro-2-fluoroaniline (CAS: 2106-05-0, Formula: ClC6H3(F)NH2, MW: 145.56) is a fluorinated aromatic amine. It serves as a vital building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique structure, featuring both chlorine and fluorine substituents on an aniline core, allows for diverse chemical transformations.

IUPAC: 5-Chloro-2-fluorophenylamine

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5-Chloro-2-fluoroaniline (ClC6H3(F)NH2) — chemical structure, CAS 2106-05-0; Chemistry, fine chemical supplied by Tech Serve Solutions

AminesBuilding BlocksChemical SynthesisFluorinated Building BlocksNitrogen CompoundsOrganic Building Blocks

01 /Applications

Pharmaceutical Intermediate

Utilised in the synthesis of active pharmaceutical ingredients (APIs), leveraging its halogenated aniline structure for targeted drug development.

Agrochemical Synthesis

A key precursor in the creation of novel pesticides and herbicides, contributing to the advancement of agricultural science.

Organic Synthesis Building Block

Employed in academic and industrial research for the construction of complex organic molecules due to its reactive amine and aryl halide functionalities.

Material Science

Potential applications in the synthesis of specialized polymers and advanced materials requiring specific electronic or physical properties.

02 /Properties

Molecular weight	145.56
Linear formula	ClC6H3(F)NH2
Assay	97%
Boiling point	102-105 °C/20 mmHg(lit.)
Density	1.29 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.561(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	103 °C / 217.4 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2106-05-0

MDL number

MFCD00069416

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Chloro-2-fluoroaniline used for?

5-Chloro-2-fluoroaniline is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also employed in material science research.

What is the CAS number and chemical formula for 5-Chloro-2-fluoroaniline?

The CAS number is 2106-05-0, and the chemical formula is ClC6H3(F)NH2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 5-Chloro-2-fluoroaniline with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

What are the primary safety hazards associated with 5-Chloro-2-fluoroaniline?

5-Chloro-2-fluoroaniline is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and gloves, must be worn when handling.