Isobutylmagnesium chloride solution
Isobutylmagnesium chloride solution (CAS: 5674-02-2) is an organometallic compound and a Grignard reagent. Supplied as a 2.0 M solution in tetrahydrofuran (THF), it serves as a versatile building block in organic synthesis. Its reactivity allows for the formation of new carbon-carbon bonds, making it valuable in the preparation of complex molecules across various chemical industries. This reagent requires careful handling due to its pyrophoric and water-reactive nature.
Organic Synthesis Intermediate
As a Grignard reagent, isobutylmagnesium chloride solution is a key nucleophile for forming carbon-carbon bonds. It is widely employed in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals.
Organometallic Chemistry
This compound is integral to organometallic chemistry, enabling the introduction of the isobutyl group into various organic substrates. It facilitates transformations like alkylation and addition reactions.
Reagent in Complex Molecule Construction
Its utility extends to the construction of complex molecular architectures. The controlled reactivity of this Grignard reagent allows for precise synthetic outcomes in multi-step syntheses.
| Molecular weight | 116.87 |
|---|---|
| Linear formula | (CH3)2CHCH2MgCl |
| Boiling point | 65-67 °C |
| Density | 0.967 g/mL at 25 °C |
| Concentration | 2.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H260In contact with water releases flammable gases
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P223Do not allow contact with water
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P370In case of fire
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -40 °C / -40 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-17-19-22-34-67 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isobutylmagnesium chloride solution used for?
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Isobutylmagnesium chloride solution is primarily used as a Grignard reagent in organic synthesis for forming carbon-carbon bonds and introducing the isobutyl group into molecules. It is a key intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals.
What are the CAS number and formula for Isobutylmagnesium chloride solution?
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The CAS number for Isobutylmagnesium chloride solution is 5674-02-2, and its linear formula is (CH3)2CHCH2MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Isobutylmagnesium chloride solution as a 2.0 M solution in THF. This is a technical/research grade reagent; TSS does not represent it as USP, BP, or EP grade.
How should Isobutylmagnesium chloride solution be handled safely?
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Isobutylmagnesium chloride solution is highly flammable, pyrophoric (ignites spontaneously in air), and reacts violently with water. It is corrosive and can cause severe skin burns and eye damage. Handle under an inert atmosphere (e.g., nitrogen or argon), wear appropriate personal protective equipment including gloves, eye protection, and respiratory protection, and keep away from ignition sources and water.
Is Isobutylmagnesium chloride solution a controlled substance?
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The provided data does not indicate that Isobutylmagnesium chloride solution is a controlled substance.
How is Isobutylmagnesium chloride solution packed and shipped?
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Isobutylmagnesium chloride solution is typically packed in containers suitable for air-sensitive and flammable reagents and shipped in compliance with regulations for hazardous materials. TSS exports globally, adhering to all relevant shipping and customs requirements.
How can I request a sample or quote for Isobutylmagnesium chloride solution?
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To request a sample or a quote for Isobutylmagnesium chloride solution, please contact our sales team via the website or direct inquiry. Provide your specific requirements, including quantity and delivery location.
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