4,4-Difluoro-L-prolinamide hydrochloride
(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride (CAS: 426844-51-1) is a fluorinated heterocyclic building block with a molecular weight of 186.59 g/mol. This chiral compound is valuable in asymmetric synthesis and organic chemical synthesis. It serves as a key intermediate for the development of novel pharmaceutical compounds and complex organic molecules, offering unique structural and electronic properties due to the presence of fluorine atoms within the pyrrolidine ring. Tech Serve Solutions supplies this chemical with an assay of 97%.
- IUPAC
- (S)-4,4-Difluoropyrolidine-2-carboxamide hydrochloride
- Synonyms
- C5H9ClF2N2O
Chiral Building Block
Utilised in asymmetric synthesis, this compound provides a chiral scaffold for constructing complex stereospecific molecules essential in pharmaceutical research and development.
Fluorinated Intermediate
The incorporation of fluorine atoms can significantly modulate the pharmacokinetic and pharmacodynamic properties of drug candidates. This makes 4,4-Difluoro-L-prolinamide hydrochloride a useful intermediate for introducing fluorine into bioactive molecules.
Organic Synthesis
Serves as a versatile building block in general organic synthesis, enabling the creation of diverse heterocyclic compounds with specific functional group arrangements.
| Molecular weight | 186.59 |
|---|---|
| Empirical formula | C5H9ClF2N2O |
| Assay | 97% |
| Optical activity | [α]/D −23±5°, c = 0.5 in H2O |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride used for?
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(S)-4,4-Difluoropyrrolidine-2-carboxamide hydrochloride is primarily used as a chiral building block in asymmetric synthesis and organic chemical synthesis, particularly for the development of pharmaceutical intermediates and novel organic molecules.
What is the CAS number and empirical formula for this compound?
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The CAS number is 426844-51-1 and the empirical formula is C5H9ClF2N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. TSS does not represent this chemical as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations for handling this chemical?
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This compound is classified as a Warning with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can ship this product worldwide.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales team through the website or by phone.
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