4,4-Difluoro-1-(2-furyl)butanedione
4,4-Difluoro-1-(2-furyl)butanedione (CAS: 480438-97-9) is a difluorinated diketone and a furan derivative. With a molecular weight of 188.13 g/mol, it serves as a valuable building block in organic synthesis. Its unique structure, featuring both a furan ring and geminal difluoro groups, makes it useful for introducing fluorine atoms and heterocyclic moieties into target molecules, particularly in the development of novel compounds and materials.
- Synonyms
- C8H6F2O34,4-Difluoro-1-(furan-2-yl)butane-1,3-dione

Organic Synthesis Intermediate
This compound acts as a versatile intermediate for the synthesis of more complex organic molecules. The presence of the diketone functionality and the difluoro substitution allows for various chemical transformations.
Fluorine Chemistry
It is used in reactions where the introduction of geminal difluoro groups into organic structures is desired. This is crucial for modifying the physicochemical properties of target compounds, such as lipophilicity and metabolic stability.
Heterocyclic Chemistry
As a furan derivative, it is employed in the construction and modification of heterocyclic ring systems. Such structures are prevalent in pharmaceuticals and agrochemicals.
| Molecular weight | 188.13 |
|---|---|
| Empirical formula | C8H6F2O3 |
| Assay | 97% |
| Melting point | 36-41 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4-Difluoro-1-(2-furyl)butanedione used for?
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4,4-Difluoro-1-(2-furyl)butanedione is primarily used as a building block and intermediate in organic synthesis, particularly in fluorine chemistry and heterocyclic chemistry for the development of novel compounds.
What is the CAS number and formula for this compound?
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The CAS number is 480438-97-9 and the empirical formula is C8H6F2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4-Difluoro-1-(2-furyl)butanedione with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4,4-Difluoro-1-(2-furyl)butanedione be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet for comprehensive handling information.
Is this compound a controlled substance?
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The provided data does not indicate that 4,4-Difluoro-1-(2-furyl)butanedione is a controlled substance.
How is 4,4-Difluoro-1-(2-furyl)butanedione packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Packaging and shipping procedures adhere to international regulations for chemical transport.
How can I request a quote or sample?
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To request a quote or a sample of 4,4-Difluoro-1-(2-furyl)butanedione, please use the contact form on our website or contact our sales department directly.
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