4,4-Difluoro-1-methylpiperidine
4,4-Difluoro-1-methylpiperidine (CAS: 1186194-60-4), with the molecular formula C6H11F2N and a molecular weight of 135.16 g/mol, is a fluorinated heterocyclic building block. This compound is characterised by its piperidine ring substituted with two fluorine atoms at the 4-position and a methyl group. It serves as a valuable intermediate in organic synthesis, particularly for the introduction of difluoromethylpiperidine moieties into more complex molecules.
- Synonyms
- C6H11F2N
Organic Synthesis Intermediate
Utilised as a versatile building block in the synthesis of novel organic compounds, especially those requiring fluorinated heterocyclic scaffolds. Its structure is amenable to further functionalisation in multi-step synthetic routes.
Pharmaceutical Research
A key intermediate for the development of potential drug candidates, where the difluoromethylpiperidine motif can influence pharmacokinetic and pharmacodynamic properties. It is employed in medicinal chemistry programmes.
Agrochemical Development
Applied in the creation of new agrochemical agents, such as pesticides or herbicides, where fluorine incorporation can enhance biological activity and stability.
Material Science Applications
Investigated for potential use in the development of advanced materials, leveraging the unique electronic and physical properties conferred by the fluorinated heterocycle.
| Molecular weight | 135.16 |
|---|---|
| Empirical formula | C6H11F2N |
| Assay | 95% |
| Density | 1.054 g/mL at 25 °C |
| Refractive index | n20/D 1.403 |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 21 °C / 69.8 °F |
|---|---|
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4-Difluoro-1-methylpiperidine used for?
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4,4-Difluoro-1-methylpiperidine is used as a building block in organic synthesis, particularly in pharmaceutical and agrochemical research, to introduce difluoromethylpiperidine moieties into target molecules.
What are the CAS number and formula for 4,4-Difluoro-1-methylpiperidine?
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The CAS number is 1186194-60-4 and the molecular formula is C6H11F2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4-Difluoro-1-methylpiperidine with an assay of 95%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.
What are the safety and handling considerations for 4,4-Difluoro-1-methylpiperidine?
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This compound is highly flammable (H225) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources.
Is 4,4-Difluoro-1-methylpiperidine a controlled substance?
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The provided data does not indicate that 4,4-Difluoro-1-methylpiperidine is a controlled substance.
How is 4,4-Difluoro-1-methylpiperidine packed, shipped, and exported?
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4,4-Difluoro-1-methylpiperidine is packed according to UN 1993 BF 3 / PG II regulations for flammable liquids. TSS exports globally, adhering to all relevant international shipping and customs regulations.
How can I request a sample or quote for 4,4-Difluoro-1-methylpiperidine?
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Please contact our sales team via the website or direct email to request a sample or a quotation for 4,4-Difluoro-1-methylpiperidine.
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