4,4-Difluorocyclohexanemethanol
4,4-Difluorocyclohexanemethanol (CAS: 178312-48-6), with the molecular formula C7H12F2O and a molecular weight of 150.17 g/mol, is a fluorinated organic building block. This compound is valuable in chemical synthesis due to the presence of the difluorocyclohexane moiety and a primary alcohol functional group. It serves as a versatile intermediate for the development of complex molecules and novel materials in research and industrial applications.
- IUPAC
- (4,4-Difluorocyclohexyl)methanol,4,4-Difluorocyclohexane-1-methanol
- Synonyms
- C7H12F2O(4,4-Difluorocyclohexyl)methanol4,4-Difluorocyclohexane-1-methanol

Fluorinated Building Block
Utilised in organic synthesis as a key intermediate for introducing the 4,4-difluorocyclohexyl group into target molecules. Its structure is useful for modifying the lipophilicity and metabolic stability of pharmaceutical candidates.
Material Science Research
This compound can be employed in the synthesis of novel polymers and advanced materials where the incorporation of fluorine atoms can impart unique physical and chemical properties.
Agrochemical Development
Serves as a building block for the creation of new agrochemical compounds, potentially influencing their efficacy and environmental profile.
| Molecular weight | 150.17 |
|---|---|
| Empirical formula | C7H12F2O |
| Assay | 97% |
| Boiling point | 207-213 °C/760 mmHg |
| Density | 1.154 g/mL at 25 °C |
| Refractive index | n20/D 1.431 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 101 °C / 213.8 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4-Difluorocyclohexanemethanol used for?
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4,4-Difluorocyclohexanemethanol is primarily used as a fluorinated building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and materials science research.
What is the CAS number and formula for 4,4-Difluorocyclohexanemethanol?
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The CAS number is 178312-48-6 and the empirical formula (Hill Notation) is C7H12F2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4-Difluorocyclohexanemethanol with an assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should 4,4-Difluorocyclohexanemethanol be handled safely?
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According to GHS, 4,4-Difluorocyclohexanemethanol is a Warning substance with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment in a well-ventilated area.
Is this product exported globally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4,4-Difluorocyclohexanemethanol.
How can I request a sample or quote for 4,4-Difluorocyclohexanemethanol?
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Please contact our sales team via the website or direct email to request a sample or a quotation for 4,4-Difluorocyclohexanemethanol.
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