Azaserine

CAS 115-02-6C5H7N3O4Biochemicals & Reagents

Azaserine (CAS: 115-02-6), with the chemical formula C5H7N3O4 and a molecular weight of 173.13 g/mol, is a biochemical compound classified as an amino acid derivative and an antibiotic. It functions as an inhibitor of certain enzymes, notably glutamine antagonists. Azaserine is specifically utilised in cell culture techniques for selecting mutant cells, such as HGPRT revertants, and is suitable for hybridoma applications.

IUPAC: O-Diazoacetyl-L-serine
Synonyms: O-Diazoacetyl-L-serine

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Azaserine (C5H7N3O4) — chemical structure, CAS 115-02-6; Life Science, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAntibioticsAntibiotics A to ZAntibiotics A-FAntibiotics by ApplicationAntifungalBiochemicals and ReagentsChemical Structure ClassInhibits an EnzymeMechanism of Action

01 /Applications

Cell Culture for Mutant Selection

Azaserine is employed in cell culture media to select for specific cellular mutations, particularly HGPRT (hypoxanthine-guanine phosphoribosyltransferase) revertants. Its enzymatic inhibitory properties are key to this selection process.

Hybridoma Technology

This compound is suitable for use in hybridoma technology. Hybridomas are crucial for producing monoclonal antibodies, and Azaserine can play a role in certain stages of their development or selection.

Biochemical Research

As a known enzyme inhibitor, Azaserine is used in biochemical research to study metabolic pathways and enzyme functions, particularly those involving glutamine metabolism.

02 /Properties

Molecular weight	173.13
Empirical formula	C5H7N3O4
Storage temperature	−20°C
Impurities tested	endotoxin, tested
Application	Used in cell culture for the selection of HGPRT revertants.
Suitability	suitable for hybridoma

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H301Toxic if swallowed
H351Suspected of causing cancer

Precautionary statements

P281Use personal protective equipment as required
P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3462 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25-40
Safety statements (S)	53-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

115-02-6

MDL number

MFCD00036802

PubChem substance

24890830

Beilstein registry

1726602

05 /Additional specifications

Sterility	γ-irradiated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Azaserine used for?

Azaserine is primarily used in cell culture for the selection of HGPRT revertants and is suitable for hybridoma applications. It also serves as an enzyme inhibitor in biochemical research.

What is the CAS number and formula for Azaserine?

The CAS number for Azaserine is 115-02-6, and its chemical formula is C5H7N3O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Azaserine as indicated by the available specifications. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.

How should Azaserine be handled safely?

Azaserine is classified with Danger signal word and carries H301 (Toxic if swallowed) and H351 (Suspected of causing cancer) hazard statements. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area and follow all safety precautions, including P281 (Use personal protective equipment as required) and P301 + P310 (IF SWALLOWED: Immediately call a POISON CENTER/doctor).