Azathioprine
Azathioprine (CAS: 446-86-6), a purine analogue with the molecular formula C9H7N7O2S and molecular weight 277.26 g/mol, functions as an enzyme inhibitor. It is widely recognised for its applications in biochemical research, particularly in studies involving enzyme mechanisms and cellular processes. This compound serves as a valuable substrate analog in enzymatic studies, aiding in the investigation of enzyme kinetics and inhibition pathways.
- IUPAC
- 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
- Synonyms
- 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
Enzyme Inhibition Studies
Azathioprine acts as an effective enzyme inhibitor, making it a crucial tool for researchers studying enzyme kinetics and mechanisms. Its structure allows it to mimic natural substrates, facilitating in-depth analysis of enzyme active sites and inhibition pathways.
Biochemical Research
As a biochemical reagent, Azathioprine is utilised in various laboratory settings for fundamental research. It is employed to investigate complex biological pathways and cellular responses where enzyme activity plays a pivotal role.
Substrate Analog Research
The compound's utility as a substrate analog assists scientists in understanding enzyme specificity and function. By interacting with enzymes, it helps elucidate crucial aspects of biological catalysis and molecular interactions.
| Molecular weight | 277.26 |
|---|---|
| Empirical formula | C9H7N7O2S |
| Assay | ≥98% |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-22-36/37/38 |
| Safety statements (S) | 22-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Azathioprine primarily used for in research?
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Azathioprine is primarily used in biochemical research as an enzyme inhibitor and substrate analog to study enzyme kinetics and biological pathways.
What is the CAS number and molecular formula for Azathioprine?
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The CAS number for Azathioprine is 446-86-6, and its molecular formula is C9H7N7O2S.
What grade and purity does Tech Serve Solutions supply for Azathioprine?
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Tech Serve Solutions supplies Azathioprine with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
How should Azathioprine be handled safely?
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Azathioprine is classified as dangerous. Handle with extreme caution, using appropriate personal protective equipment including eyeshields, face shields, gloves, and a suitable respirator. Avoid inhalation, ingestion, and contact with skin and eyes. Always consult the Safety Data Sheet (SDS) before use.
Is Azathioprine a controlled substance?
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Based on the provided data, Azathioprine is not explicitly listed as a controlled substance. However, its hazard profile (H350 - May cause cancer) necessitates careful handling and regulatory awareness.
How is Azathioprine typically packed and shipped?
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Azathioprine is typically packed in secure containers suitable for chemical transport and is exported globally by Tech Serve Solutions following all necessary regulations.
How can I request a sample or quote for Azathioprine?
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To request a sample or quote for Azathioprine, please contact our sales team through the website or by phone, providing your specific requirements.
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