o-Toluenesulfonyl isocyanate
o-Toluenesulfonyl isocyanate (CAS: 32324-19-9), with the molecular formula CH3C6H4SO2NCO and a molecular weight of 197.21 g/mol, is a reactive organic compound. It serves as a valuable building block in chemical synthesis, particularly for introducing the o-toluenesulfonyl moiety. Its applications span various sectors of organic chemistry and materials science. TSS ensures high standards for this chemical intermediate.
Organic Synthesis Reagent
o-Toluenesulfonyl isocyanate is employed as a key intermediate in the synthesis of complex organic molecules. It is particularly useful for the derivatization of amines and alcohols, forming sulfonamides and sulfonate esters, respectively.
Pharmaceutical Intermediate
This compound can be utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its reactive isocyanate group allows for versatile functionalisation in drug discovery and development pathways.
Material Science Applications
The compound's structure lends itself to applications in polymer chemistry and material science. It can be incorporated into polymer backbones or used for surface modification, altering material properties.
| Molecular weight | 197.21 |
|---|---|
| Linear formula | CH3C6H4SO2NCO |
| Assay | 95% |
| Density | 1.303 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.54(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2206 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 14-20/21/22-42 |
| Safety statements (S) | 23-26-27-28-37/39 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is o-Toluenesulfonyl isocyanate used for?
+
o-Toluenesulfonyl isocyanate is primarily used as a versatile building block and reagent in organic synthesis, including the preparation of pharmaceutical intermediates and in material science applications.
What are the CAS number and molecular formula for o-Toluenesulfonyl isocyanate?
+
The CAS number for o-Toluenesulfonyl isocyanate is 32324-19-9, and its molecular formula is CH3C6H4SO2NCO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies o-Toluenesulfonyl isocyanate with a minimum assay of 95%. TSS does not represent this product as USP, BP, or EP grade.
How should o-Toluenesulfonyl isocyanate be handled safely?
+
o-Toluenesulfonyl isocyanate is classified as Danger. It is harmful if swallowed, in contact with skin, or if inhaled, and can cause respiratory irritation. It also reacts violently with water. Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be worn. Handle only in a well-ventilated area.
Is o-Toluenesulfonyl isocyanate a controlled substance?
+
The provided data does not indicate that o-Toluenesulfonyl isocyanate is a controlled substance.
How is o-Toluenesulfonyl isocyanate packed and shipped?
+
o-Toluenesulfonyl isocyanate is shipped according to UN 2206, hazard class 6.1, packing group III regulations. TSS adheres to all international shipping and export regulations for chemical compounds.
How can I request a quote or sample for o-Toluenesulfonyl isocyanate?
+
To request a quote or sample for o-Toluenesulfonyl isocyanate, please contact our sales team through the TSS website or by telephone. Our team will be happy to assist you with your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis