o-Toluenesulfonyl chloride
o-Toluenesulfonyl chloride (CAS: 133-59-5), with the molecular formula CH3C6H4SO2Cl and a molecular weight of 190.65 g/mol, is a key organic building block. This sulfur compound, classified as a sulfonyl halide, is primarily utilized in chemical synthesis. Its properties make it a valuable intermediate for creating more complex organic molecules in various research and industrial applications.
Organic Synthesis Intermediate
o-Toluenesulfonyl chloride serves as a crucial reagent in organic synthesis. It is employed to introduce the o-toluenesulfonyl group into various molecules, facilitating the formation of sulfonamides, sulfonates, and other sulfur-containing derivatives.
Pharmaceutical and Agrochemical Research
This compound is a valuable building block in the research and development of new pharmaceutical agents and agrochemicals. Its structure allows for modification and incorporation into novel active compounds.
Dye and Pigment Chemistry
In certain specialised areas of dye and pigment manufacturing, o-toluenesulfonyl chloride can act as an intermediate for the synthesis of specific colorants.
| Molecular weight | 190.65 |
|---|---|
| Linear formula | CH3C6H4SO2Cl |
| Assay | 97% |
| Boiling point | 254 °C(lit.) |
| Density | 1.320 g/mL at 25 °C(lit.) |
| Refractive index | n20/D >1.5580(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is o-Toluenesulfonyl chloride used for?
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o-Toluenesulfonyl chloride (CAS: 133-59-5) is primarily used as an intermediate in organic synthesis for introducing the o-toluenesulfonyl group into molecules, finding applications in pharmaceutical, agrochemical, and dye research.
What is the CAS number and molecular formula for o-Toluenesulfonyl chloride?
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The CAS number for o-Toluenesulfonyl chloride is 133-59-5, and its molecular formula is CH3C6H4SO2Cl.
What grade and purity does Tech Serve Solutions supply for o-Toluenesulfonyl chloride?
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Tech Serve Solutions supplies o-Toluenesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should o-Toluenesulfonyl chloride be handled?
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o-Toluenesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires full protective equipment, including faces shields, goggles, gloves, and appropriate respiratory protection. Always consult the Safety Data Sheet (SDS) before use.
How is o-Toluenesulfonyl chloride packed and exported?
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o-Toluenesulfonyl chloride is shipped according to UN 3265, 8/PGII regulations, ensuring safe and compliant transport for export.
How can I request a quote or sample for o-Toluenesulfonyl chloride?
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To request a quote or sample of o-Toluenesulfonyl chloride, please contact our sales team through the website or via the provided contact details.
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