Cyclobutylamine
Cyclobutylamine (CAS: 2516-34-9; Formula: C4H7NH2; MW: 71.12) is a primary aliphatic amine with a cyclobutyl ring. This versatile organic building block is characterised by its liquid state at room temperature and is primarily utilised in chemical synthesis and research applications. Its structure makes it a valuable intermediate for the creation of more complex organic molecules, particularly within the pharmaceutical and agrochemical sectors.
- IUPAC
- Aminocyclobutane
- Synonyms
- Aminocyclobutane

Pharmaceutical Intermediate
Cyclobutylamine serves as a key building block in the synthesis of various pharmaceutical compounds. Its unique cyclobutyl structure can be incorporated into drug candidates to modify their pharmacokinetic and pharmacodynamic properties.
Agrochemical Synthesis
This amine is employed in the development of novel agrochemicals. It can be used to construct active ingredients in pesticides, herbicides, and fungicides, contributing to crop protection and agricultural innovation.
Organic Synthesis Reagent
As a reactive primary amine, cyclobutylamine is a valuable reagent in general organic synthesis. It participates in a variety of reactions, including nucleophilic additions, alkylations, and condensation reactions, facilitating the construction of diverse molecular frameworks.
Research and Development
Cyclobutylamine is utilised in academic and industrial research laboratories for exploring new chemical reactions and developing novel materials. Its availability supports fundamental research in organic chemistry.
| Molecular weight | 71.12 |
|---|---|
| Linear formula | C4H7NH2 |
| Assay | 98% |
| Boiling point | 81.5 °C/752 mmHg(lit.) |
| Density | 0.833 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.437(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -4 °C / 24.8 °F |
| Transport (UN / ADR) | UN 2733 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclobutylamine used for?
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Cyclobutylamine is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also used in research and development laboratories.
What is the CAS number and formula for Cyclobutylamine?
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The CAS number for Cyclobutylamine is 2516-34-9, and its chemical formula is C4H7NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cyclobutylamine with an assay of 98%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Cyclobutylamine be handled and stored safely?
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Cyclobutylamine is a Danger hazard. It is flammable (flash point -4 °C) and causes severe skin burns and eye damage. Handle with extreme caution using appropriate personal protective equipment, including full-face protection, gloves, and a suitable respirator. Store in a cool, well-ventilated area at 2-8°C, away from ignition sources.
Can Tech Serve Solutions export Cyclobutylamine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including Cyclobutylamine.
How can I request a quote or sample of Cyclobutylamine?
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To request a quote or sample of Cyclobutylamine, please contact our sales team through the website or by phone.
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