4,4-Difluoropiperidine hydrochloride
4,4-Difluoropiperidine hydrochloride (CAS: 144230-52-4), a valuable fluorinated heterocyclic building block, offers enhanced lipophilicity and metabolic stability in organic synthesis. With a molecular formula of C5H9F2N · HCl and a molecular weight of 157.59 g/mol, this compound is instrumental in the development of novel pharmaceuticals and agrochemicals. Its unique difluorinated piperidine structure makes it a sought-after intermediate for creating complex molecular architectures.
- Synonyms
- C5H9F2N · HCl
Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the difluoropiperidine moiety can improve pharmacokinetic properties such as bioavailability and metabolic resistance.
Agrochemical Development
Serves as a key building block for novel pesticides, herbicides, and fungicides, leveraging fluorine's impact on biological activity and environmental persistence.
Material Science
Incorporated into the design of advanced materials, contributing unique electronic or physical properties due to the presence of fluorine atoms.
Chemical Synthesis
A versatile reagent for introducing the 4,4-difluoropiperidine group into various organic molecules, facilitating complex chemical transformations.
| Molecular weight | 157.59 |
|---|---|
| Empirical formula | C5H9F2N · HCl |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 173-177 °C |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4-Difluoropiperidine hydrochloride used for?
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4,4-Difluoropiperidine hydrochloride is primarily used as a building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries, for the development of novel compounds with improved properties.
What are the CAS number and formula for 4,4-Difluoropiperidine hydrochloride?
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The CAS number is 144230-52-4, and the formula is C5H9F2N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4-Difluoropiperidine hydrochloride with an assay of 97%. This product is suitable for research and chemical synthesis and is not represented as USP, BP, or EP grade.
How should 4,4-Difluoropiperidine hydrochloride be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. This compound is classified as an irritant (H319) and should be handled in a well-ventilated area. In case of eye contact, rinse cautiously with water for several minutes.
Is 4,4-Difluoropiperidine hydrochloride a controlled substance?
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The provided data does not indicate that 4,4-Difluoropiperidine hydrochloride is a controlled substance.
How is 4,4-Difluoropiperidine hydrochloride shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product can be packed and shipped according to international regulations for chemical transport.
How can I request a sample or quote for 4,4-Difluoropiperidine hydrochloride?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone.
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