4,4-Difluorocyclohexanol
4,4-Difluorocyclohexanol (CAS: 22419-35-8) is a fluorinated organic compound with the molecular formula C6H10F2O and a molecular weight of 136.14 g/mol. This cyclohexanol derivative is characterised by the presence of two fluorine atoms at the 4-position, imparting unique chemical properties. It serves as a valuable building block in organic synthesis, particularly in the development of novel fluorinated molecules for pharmaceutical and material science applications. It is supplied by TSS with an assay of 95%.
- Synonyms
- C6H10F2O

Fluorinated Building Block
4,4-Difluorocyclohexanol is utilised as a key intermediate in the synthesis of complex organic molecules. Its difluorinated structure makes it ideal for introducing fluorine atoms into target compounds, which can significantly alter their pharmacokinetic or material properties.
Pharmaceutical Intermediate
This compound is employed in the research and development of new pharmaceutical agents. The incorporation of fluorine can enhance metabolic stability, lipophilicity, and binding affinity of drug candidates.
Material Science
The unique properties conferred by the geminal difluoro group make 4,4-Difluorocyclohexanol a useful component in the design of advanced materials, such as fluoropolymers or liquid crystals.
| Molecular weight | 136.14 |
|---|---|
| Empirical formula | C6H10F2O |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 60-65 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4-Difluorocyclohexanol used for?
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4,4-Difluorocyclohexanol is primarily used as a building block in organic synthesis, especially for the development of fluorinated compounds for pharmaceutical and material science applications.
What are the CAS number and molecular formula for 4,4-Difluorocyclohexanol?
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The CAS number for 4,4-Difluorocyclohexanol is 22419-35-8, and its molecular formula is C6H10F2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4-Difluorocyclohexanol with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 4,4-Difluorocyclohexanol be handled and stored?
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Handle 4,4-Difluorocyclohexanol with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection. It is recommended to store the compound at 2-8°C, away from incompatible materials, as it can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
Is 4,4-Difluorocyclohexanol a controlled substance?
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The provided data does not indicate that 4,4-Difluorocyclohexanol is a controlled substance.
How is 4,4-Difluorocyclohexanol packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and handling for chemical shipments in compliance with international regulations. Specific details for packing and shipping can be provided upon request.
How can I request a quote or sample for 4,4-Difluorocyclohexanol?
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To request a quote or sample of 4,4-Difluorocyclohexanol, please contact the Tech Serve Solutions sales department through our official channels.
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