3-Fluorobenzonitrile
3-Fluorobenzonitrile (CAS: 403-54-3, Formula: FC6H4CN, MW: 121.11) is a valuable organic compound. This fluorinated benzonitrile derivative serves as a key intermediate and building block in organic synthesis. Its primary applications lie in the development of novel molecules, particularly within the pharmaceutical and agrochemical sectors, where the introduction of a fluorinated aromatic ring is often desired for modulating biological activity.
Synthesis of Advanced Materials
3-Fluorobenzonitrile can be employed in the synthesis of specialised polymers and advanced materials. Its unique structure allows for the creation of materials with tailored electronic or thermal properties.
Pharmaceutical Intermediate
This compound acts as a crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs). The presence of the fluorine atom and the nitrile group offers versatile reactivity for medicinal chemistry applications.
Agrochemical Research
In agrochemical development, 3-Fluorobenzonitrile can be utilised as a precursor for novel pesticides, herbicides, or fungicides. The fluorine substituent can enhance the efficacy or metabolic stability of the final agrochemical product.
Preparation of Bis(3-cyanophenoxy)phenylenes
Historically, 3-Fluorobenzonitrile has been utilised in the preparation of bis(3-cyanophenoxy)phenylenes, demonstrating its utility in constructing complex organic architectures.
| Molecular weight | 121.11 |
|---|---|
| Linear formula | FC6H4CN |
| Assay | 98% |
| Boiling point | 182-183 °C/753 mmHg(lit.) |
| Density | 1.133 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5043(lit.) |
| Application | 3-Fluorobenzonitrile has been used in the preparation of bis(3-cyanophenoxy)phenylenes1. |
| Melting point | −16 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 68 °C / 154.4 °F |
| Transport (UN / ADR) | UN 3276 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluorobenzonitrile used for?
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3-Fluorobenzonitrile is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and chemical formula for 3-Fluorobenzonitrile?
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The CAS number for 3-Fluorobenzonitrile is 403-54-3, and its chemical formula is FC6H4CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluorobenzonitrile with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 3-Fluorobenzonitrile be handled safely?
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3-Fluorobenzonitrile is a hazardous substance. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Always wear appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves, and use in a well-ventilated area or with a suitable respirator.
Is 3-Fluorobenzonitrile shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Fluorobenzonitrile, and can arrange for export worldwide.
How can I request a quote or sample for 3-Fluorobenzonitrile?
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To request a quote or sample for 3-Fluorobenzonitrile, please contact our sales team through the website or by phone.
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