3-Fluorobenzyl bromide
3-Fluorobenzyl bromide (CAS: 456-41-7) is an organohalogen compound with the formula FC6H4CH2Br and a molecular weight of 189.02 g/mol. This fluorinated aromatic building block is a key intermediate in organic synthesis. It is utilised in the chemical industry for the preparation of more complex molecules, particularly in the development of pharmaceuticals and agrochemicals, owing to the reactivity of the benzyl bromide functional group and the influence of the fluorine atom on molecular properties.
- IUPAC
- α-Bromo-3-fluorotoluene
- Synonyms
- α-Bromo-3-fluorotoluene3-Fluorobenzyl bromide
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The introduction of the fluorobenzyl moiety can modulate pharmacokinetic and pharmacodynamic properties.
Agrochemical Synthesis
Serves as a building block for creating novel pesticides, herbicides, and fungicides. Fluorinated compounds often exhibit enhanced biological activity and stability.
Organic Synthesis Reagent
A versatile reagent for introducing the 3-fluorobenzyl group into various organic molecules via alkylation reactions. It is valuable in research and development for novel compound discovery.
Material Science Research
Employed in the development of new materials where fluorinated aromatic structures are required to impart specific electronic or physical properties.
| Molecular weight | 189.02 |
|---|---|
| Linear formula | FC6H4CH2Br |
| Assay | 99% |
| Boiling point | 88 °C/20 mmHg(lit.) |
| Density | 1.541 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.546(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 23-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluorobenzyl bromide used for?
+
3-Fluorobenzyl bromide is primarily used as a chemical intermediate in organic synthesis, particularly for the preparation of pharmaceuticals, agrochemicals, and advanced materials. It functions as a building block to introduce the 3-fluorobenzyl group into target molecules.
What is the CAS number and chemical formula for 3-Fluorobenzyl bromide?
+
The CAS number for 3-Fluorobenzyl bromide is 456-41-7, and its chemical formula is FC6H4CH2Br.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Fluorobenzyl bromide with a minimum assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Fluorobenzyl bromide be handled safely?
+
3-Fluorobenzyl bromide is a corrosive substance that causes severe skin burns and eye damage and may cause respiratory irritation (H314, H335). Handle with appropriate personal protective equipment, including gloves, eye protection (goggles, face shield), and respiratory protection in a well-ventilated area or fume hood. Refer to the safety data sheet for comprehensive handling information.
Is 3-Fluorobenzyl bromide controlled or scheduled?
+
The provided data does not indicate that 3-Fluorobenzyl bromide is a controlled or scheduled substance. However, users should always verify local regulations.
How is 3-Fluorobenzyl bromide packed and shipped?
+
3-Fluorobenzyl bromide is shipped as a UN 3265, Class 8, Packing Group II corrosive material. Packaging adheres to stringent international regulations for the safe transport of hazardous chemicals. TSS is an experienced global exporter.
How can I request a quote or sample for 3-Fluorobenzyl bromide?
+
To request a quote or a sample of 3-Fluorobenzyl bromide, please contact our sales department through the website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis