3-Fluorobenzylamine
3-Fluorobenzylamine (CAS: 100-82-3) is an organic compound with the formula FC6H4CH2NH2 and a molecular weight of 125.14 g/mol. As a fluorinated building block and an amine, it serves as a valuable intermediate in organic synthesis. Its applications include research into reaction kinetics and the synthesis of complex pharmaceutical agents.
Reaction Kinetics Studies
3-Fluorobenzylamine has been utilised in research to investigate the reaction rates between benzylamines and electrophilic reagents such as 1-Chloro-2,4-dinitrobenzene and toluene-p-sulphonyl chloride.
Pharmaceutical Intermediate
The compound serves as a building block in the synthesis of novel pharmaceutical compounds, notably in the development of substituted amino-sulfonamide protease inhibitors.
Organic Synthesis
As a fluorinated aryl building block, 3-Fluorobenzylamine is employed in the construction of more complex organic molecules, contributing to advancements in medicinal chemistry and materials science.
| Molecular weight | 125.14 |
|---|---|
| Linear formula | FC6H4CH2NH2 |
| Assay | 97% |
| Density | 1.097 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.514(lit.) |
| Application | 3-Fluorobenzylamine has been used to study the rate of reaction of benzylamines with 1-Chloro-2,4-dinitrobenzene and toluene-p-sulphonyl chloride1. It has also been used in the synthesis of substituted amino-sulfonamide protease inhibitors (PIs) DPC 681 and DPC 6842. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluorobenzylamine used for?
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3-Fluorobenzylamine is used in chemical synthesis, including studies of reaction kinetics and as an intermediate in the preparation of pharmaceutical compounds like protease inhibitors.
What is the CAS number and chemical formula for 3-Fluorobenzylamine?
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The CAS number is 100-82-3, and the linear formula is FC6H4CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluorobenzylamine with a minimum assay of 97%. This product is suitable for research and general chemical synthesis; it is not supplied as USP, EP, or BP grade.
What are the safety precautions for handling 3-Fluorobenzylamine?
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3-Fluorobenzylamine is a corrosive substance (H314). Handle with appropriate personal protective equipment, including chemical-resistant gloves, eye protection (goggles, face shield), and respiratory protection if needed. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing. In case of exposure, follow emergency procedures as indicated by the safety data sheet.
How is 3-Fluorobenzylamine packed and shipped?
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3-Fluorobenzylamine is carefully packed in accordance with international shipping regulations for hazardous materials and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for 3-Fluorobenzylamine?
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To request a quote or a sample of 3-Fluorobenzylamine, please contact the Tech Serve Solutions sales team via our website or direct email.
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