3-Fluorobenzyl chloride
3-Fluorobenzyl chloride (CAS: 456-42-8; Formula: FC₆H₄CH₂Cl; MW: 144.57) is a halogenated aromatic compound supplied by Tech Serve Solutions. This versatile organic building block is primarily utilised in chemical synthesis and as a fluorinated intermediate. Its reactive benzyl chloride moiety and the presence of fluorine make it valuable for introducing specific structural features into target molecules, particularly in research and development settings.
- IUPAC
- α-Chloro-3-fluorotoluene,1-Chloromethyl-3-fluorobenzene
- Synonyms
- α-Chloro-3-fluorotoluene1-Chloromethyl-3-fluorobenzene
Organic Synthesis Intermediate
3-Fluorobenzyl chloride serves as a key intermediate in the synthesis of more complex organic molecules. It can undergo various reactions, such as nucleophilic substitution, to incorporate the 3-fluorobenzyl group into diverse chemical structures.
Pharmaceutical Building Block
This compound is valuable in the development of novel pharmaceutical agents. The introduction of fluorine can modulate a drug candidate's pharmacokinetic and pharmacodynamic properties, making 3-Fluorobenzyl chloride a useful precursor in medicinal chemistry.
Agrochemical Research
It can be employed in the research and development of new agrochemicals. The 3-fluorobenzyl motif may contribute to the efficacy or properties of potential pesticides or herbicides.
Material Science
In material science, 3-Fluorobenzyl chloride can be used to synthesise specialised polymers or functional materials where the fluorinated aromatic structure imparts unique characteristics.
| Molecular weight | 144.57 |
|---|---|
| Linear formula | FC6H4CH2Cl |
| Assay | 96% |
| Density | 1.194 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.511(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluorobenzyl chloride used for?
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3-Fluorobenzyl chloride is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialised materials. It serves as a building block for introducing the 3-fluorobenzyl group into target molecules.
What are the CAS number and formula for 3-Fluorobenzyl chloride?
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The CAS number for 3-Fluorobenzyl chloride is 456-42-8, and its linear formula is FC₆H₄CH₂Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluorobenzyl chloride with an assay of 96%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 3-Fluorobenzyl chloride be handled safely?
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3-Fluorobenzyl chloride is classified as Danger, with hazards including flammability (H226) and severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment, including gloves, goggles, and face shields, and use in a well-ventilated area or with respiratory protection. Consult the Safety Data Sheet for full details.
Is 3-Fluorobenzyl chloride a controlled substance?
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The provided data does not indicate that 3-Fluorobenzyl chloride is a controlled substance.
How is 3-Fluorobenzyl chloride packed, shipped, and exported?
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As a global supplier, Tech Serve Solutions adheres to all relevant regulations for packing, shipping, and exporting chemical compounds like 3-Fluorobenzyl chloride, ensuring compliance for international distribution.
How can I request a quote or sample for 3-Fluorobenzyl chloride?
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To request a quote or sample for 3-Fluorobenzyl chloride, please contact our sales department through the website or by phone, providing your specific requirements and delivery details.
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