2,5-Diiodo-3-methoxypyridine
2,5-Diiodo-3-methoxypyridine (CAS: 1138444-33-3) is a halogenated pyridine derivative with the molecular formula C6H5I2NO and a molecular weight of 360.92 g/mol. As a valuable building block, it is utilised in organic synthesis, particularly in the construction of complex heterocyclic structures. Its diiodo substitution pattern offers versatile reactivity for cross-coupling reactions and further functionalization, making it a key intermediate in chemical research and development.
- Synonyms
- C6H5I2NO

Organic Synthesis Intermediate
2,5-Diiodo-3-methoxypyridine serves as a key intermediate in multi-step organic syntheses. Its strategically placed iodine atoms are amenable to various coupling reactions, such as Suzuki, Stille, or Sonogashira couplings, enabling the introduction of diverse organic fragments.
Heterocyclic Chemistry
This compound is particularly useful in the field of heterocyclic chemistry, allowing for the elaboration of pyridine scaffolds. The methoxy group and the two iodine atoms provide distinct points for regioselective modification, facilitating the synthesis of novel pyridine-based compounds.
Medicinal Chemistry Research
As a building block, 2,5-Diiodo-3-methoxypyridine can be employed in the discovery and development of new pharmaceutical agents. Pyridine cores are prevalent in many bioactive molecules, and this iodinated derivative offers a route to novel analogues.
| Molecular weight | 360.92 |
|---|---|
| Empirical formula | C6H5I2NO |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Diiodo-3-methoxypyridine used for?
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2,5-Diiodo-3-methoxypyridine is primarily used as a building block and intermediate in organic synthesis, particularly for creating complex heterocyclic structures and in medicinal chemistry research.
What is the CAS number and molecular formula for 2,5-Diiodo-3-methoxypyridine?
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The CAS number is 1138444-33-3, and its molecular formula is C6H5I2NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade chemical. The specific assay or purity is detailed in the product's Certificate of Analysis; we do not represent it as USP, BP, or EP grade.
What are the safety considerations for handling 2,5-Diiodo-3-methoxypyridine?
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Specific safety data, including GHS hazards, is provided in the Safety Data Sheet (SDS) available for this product. Users should consult the SDS for appropriate personal protective equipment and handling procedures.
How is 2,5-Diiodo-3-methoxypyridine packed and shipped?
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Products are carefully packed according to international shipping regulations and are available for export worldwide. Please contact us for specific shipping details.
How can I request a sample or quote for 2,5-Diiodo-3-methoxypyridine?
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To request a sample or a quote, please use the online inquiry form or contact our sales team directly. Please specify the required quantity and your delivery location.
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