2,5-Diiodothiophene
2,5-Diiodothiophene (CAS 625-88-7) is a halogenated heterocyclic organic compound with the molecular formula C4H2I2S and a molecular weight of 335.93 g/mol. This thiophene derivative serves as a valuable building block in organic synthesis, particularly for creating more complex molecules. Its diiodo substitution pattern makes it a useful intermediate for cross-coupling reactions and functionalisation in the development of novel materials and pharmaceuticals.
- Synonyms
- C4H2I2S2,5-Diiodo-1-thia-cyclopentadieneThiophene, 2,5-diiodo-

Organic Synthesis Intermediate
2,5-Diiodothiophene is employed as a key intermediate in the synthesis of various organic compounds. Its reactive iodine atoms facilitate diverse coupling reactions, enabling the construction of complex molecular architectures.
Materials Science Research
This compound finds application in materials science, particularly in the development of organic semiconductors and conducting polymers. Its thiophene core and iodine substituents allow for tailored electronic properties in advanced materials.
Pharmaceutical Intermediate
As a heterocyclic building block, 2,5-Diiodothiophene can be used in the multi-step synthesis of pharmaceutical candidates and active pharmaceutical ingredients (APIs), contributing to drug discovery and development.
| Molecular weight | 335.93 |
|---|---|
| Empirical formula | C4H2I2S |
| Assay | 98% |
| Boiling point | 139-140 °C(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 37-41 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Diiodothiophene used for?
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2,5-Diiodothiophene is primarily used as a building block and intermediate in organic synthesis, materials science research, and the development of pharmaceutical compounds.
What is the CAS number and formula for 2,5-Diiodothiophene?
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The CAS number for 2,5-Diiodothiophene is 625-88-7, and its molecular formula is C4H2I2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Diiodothiophene with an assay of 98%. TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling 2,5-Diiodothiophene?
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2,5-Diiodothiophene is combustible and has a high flash point. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It is classified under WGK 2 in Germany.
How is 2,5-Diiodothiophene stored and shipped?
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2,5-Diiodothiophene should be stored at 2-8°C. Tech Serve Solutions can export this chemical globally.
How can I request a quote or sample of 2,5-Diiodothiophene?
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Please contact our sales team via the website to request a quote or a sample of 2,5-Diiodothiophene.
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