1,2,3,4-Tetrahydro-1-naphthylamine
1,2,3,4-Tetrahydro-1-naphthylamine (CAS: 2217-40-5), with the molecular formula C10H13N and a molecular weight of 147.22 g/mol, is a valuable organic building block. This amine derivative is characterised by its naphthylamine structure within a saturated ring system. It is primarily utilised in chemical synthesis, particularly for the preparation of novel chiral phosphine-aminophosphine ligands, contributing to advancements in catalysis and organic chemistry.
- Synonyms
- 4-Tetrahydro-1-naphthylamine1-Amino-4-tetralin1-AminotetralinTetrahydro-1-naphthylamine

Chiral Ligand Synthesis
1,2,3,4-Tetrahydro-1-naphthylamine serves as a key precursor in the synthesis of advanced chiral phosphine-aminophosphine ligands. These ligands are critical in asymmetric catalysis for producing enantiomerically pure compounds.
Organic Synthesis Intermediate
As a versatile building block, this compound facilitates the construction of complex organic molecules. Its amine functionality allows for various derivatizations, making it useful in multi-step synthetic routes.
Research and Development
The unique structure of 1,2,3,4-Tetrahydro-1-naphthylamine makes it a compound of interest in academic and industrial research for exploring new chemical reactions and developing novel materials.
| Molecular weight | 147.22 |
|---|---|
| Empirical formula | C10H13N |
| Assay | 97% |
| Boiling point | 246-247 °C/714 mmHg(lit.) |
| Density | 1.026 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.562(lit.) |
| Application | 1,2,3,4-Tetrahydro-1-naphthylamine has been used in the preparation of new chiral phosphine-aminophosphine ligands1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,3,4-Tetrahydro-1-naphthylamine used for?
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1,2,3,4-Tetrahydro-1-naphthylamine is used in chemical synthesis, particularly for preparing chiral phosphine-aminophosphine ligands and as a general organic building block for complex molecule construction.
What are the CAS number and molecular formula?
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The CAS number for 1,2,3,4-Tetrahydro-1-naphthylamine is 2217-40-5, and its molecular formula is C10H13N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2,3,4-Tetrahydro-1-naphthylamine with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling precautions for 1,2,3,4-Tetrahydro-1-naphthylamine?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Ensure adequate ventilation, wear appropriate personal protective equipment including eyeshields and gloves, and use a suitable respirator. Avoid breathing vapours.
Is 1,2,3,4-Tetrahydro-1-naphthylamine a controlled substance?
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Based on the provided data, there is no indication that 1,2,3,4-Tetrahydro-1-naphthylamine (CAS: 2217-40-5) is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions handles the packing, shipping, and export of chemicals with adherence to international regulations, ensuring safe transit and compliance for global distribution.
How can I request a quote or sample?
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To request a quote or a sample of 1,2,3,4-Tetrahydro-1-naphthylamine, please contact the Tech Serve Solutions sales team through our official website or designated contact channels.
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